Background: Bangladesh has to carry an extensive burden of tuberculosis in varied form of presentation. In the era of minimally invasive surgery (MIS) port site tuberculosis is usually a rare incidence. Among all the infections it has been identified as a prolong burden for both patients and surgeons. This study was done to notify such rare complication of MIS and tried to find out is there really an upsurge of this infection in Bangladesh. Methods: This retrospective study was done an urban area of Bangladesh during September 2020 to June 2021. 483 laparoscopic surgeries were done by six different surgeons in 5 different hospitals during September 2020 to January 2021. All surgeons have minimum five years experiences in laparoscopic surgery. 20 minutes emersion of the laparoscopic instruments into activated glutaraldehyde solution 2% (CIDEX) was used as method of chemical sterilization. Other surgical instruments were sterilized by conventional autoclave method. Results: Among them 87 patients developed port infections. 66 (75.86%) patients of this 87 developed non-healing ulcer. Biopsy from the ulcer showed granulomatous tissue in 56 patients and the other 10 was nonspecific inflammation. CAT I anti-TB chemotherapy was initiated to all the patients and all improved by this therapy. Use of 3.54% glutaraldehyde instead of 2% or immersion of instruments for a longer period (more than 20 minutes) could be tried in larger scale to prove its efficacy. Conclusions: National tuberculosis control program (NTP) should give more emphasis on cutaneous tuberculosis as the morbidity of this disease is high. Surgeons of Bangladesh should admit and report such incidences as, if it is documented in other areas of the country, it may need to develop a national guideline to prevent and treat port site tuberculosis.

In March 2020 WHO declared COVID-19 as pandemic while April 2021 Indian authority concede to declare a significantly increased incidence of “Black Fungus” among the COVID-19 patients. The primary route of infection for Mucormycosis or fungal infection following COVID-19 is inhalation or ingestion resulting accumulation of the agents in nose, para-nasal sinuses and mouth. The spores of black fungus intrude neural and vascular structure, which cause mucosal necrosis due to thrombosis in vasculature. The extension of the disease then increases through further destruction of bones of para-nasal sinus as well as neural and vascular route dissemination. We thought about removing, neutralizing or destroying the culprit fungi from its route of entry zone, i.e. nose and mouth. Povidone Iodine (PVP-I) is a microbicidal agent having effective fungicidal as well as virucidal and bactericidal property. PVP-I can be used in both oral and nasal cavity safely. Efficacy and safety of PVP-I is proved in nose in case of COVID-19. PVP-I is proved effective against different fungi at different concentration at different site. So, we recommend Povidone Iodine nasal spray or irrigation and mouthwash for gargling for these vulnerable group of patients in large scale to prevent post-COVID mucormycosis or fungal infection. J Dhaka Med Coll. 2021; 30(2) : 176-179