Introduction: Preventive self-care behaviors such as home quarantine are very important in preventing COVID-19. The aim of this study was to explore the factors of non-compliance with home quarantine during the outbreak of COVID-19. Methods: This study was conducted with a qualitative content analysis approach in 2020 in Iran. In order to collect information, 24 samples were selected by purposive sampling method and semi-structured interviews were conducted with them. Interviews were recorded, transcribed and the collected data were analyzed using the contractual content analysis approach using Elo and Kingas method. Results: Analyzing the data revealed in six main themes and fourteen main categories, including: necessities for everyday activities and living (with subthemes providing the necessities of life, forced by work/job insecurity, need for fun/entertainment, sports), mental instability in adults/children (with subthemes of mental states, restlessness of children), spiritual and religious beliefs (with subthemes of belief in fate and immunity/disease immunity, right to know death), managerial problems/confusion (with subthemes of government mismanagement, expectations from the government, economic turmoil), marital incompatibility (with subthemes domestic violence), adherence to socio-cultural patterns (with the subthemes of sociocultural factors). Conclusion: According to the results, it should be noted that several factors are contributing to non-compliance with home quarantine that it is necessary for the relevant authorities to take measures to remove these obstacles and provide the necessary facilities.

Introduction: Preventive self-care behaviors such as home quarantine are very important in preventing COVID-19. The aim of this study was to explore the factors of non-compliance with home quarantine during the outbreak of COVID-19. Methods: This study was conducted with a qualitative content analysis approach in 2020 in Iran. In order to collect information, 24 samples were selected by purposive sampling method and semi-structured interviews were conducted with them. Interviews were recorded, transcribed and the collected data were analyzed using the contractual content analysis approach using Elo and Kingas method. Results: Analyzing the data revealed in six main themes and fourteen main categories, including: necessities for everyday activities and living (with subthemes providing the necessities of life, forced by work/job insecurity, need for fun/entertainment, sports), mental instability in adults/children (with subthemes of mental states, restlessness of children), spiritual and religious beliefs (with subthemes of belief in fate and immunity/disease immunity, right to know death), managerial problems/confusion (with subthemes of government mismanagement, expectations from the government, economic turmoil), marital incompatibility (with subthemes domestic violence), adherence to socio-cultural patterns (with the subthemes of sociocultural factors). Conclusion: According to the results, it should be noted that several factors are contributing to non-compliance with home quarantine that it is necessary for the relevant authorities to take measures to remove these obstacles and provide the necessary facilities.