<p>This study aims to analyze the effect of burden and stress on the work performance of employees of the Ministry of Religious Affairs of the Republic of Indonesia with motivation as a moderation variable. One of the main duties of the Ministry of Religious Affairs of the Republic of Indonesia is to provide services to the community related to education in the level of kindergarten to university in Indonesia. Given the large work area of employees and the heavy workload in the ministry, it is not uncommon for employees to lose motivation at work, that makes the achievement is low. 97 employees were involved in this study. Using the SEM-PLS method, the results of this study show that the indicator reliability, Cronbach alpha, composite reliability and AVE values are valid. The discriminant validity value is greater than the factor charge value. Workload negatively influences work performance either directly or indirectly, moderated by motivation. Work stress positively influences work performance directly or indirectly, moderated by motivation. Motivation has a positive influence on work performance.</p>