The development of low-volume continuous processes for the pharmaceutical industry requires a greater understanding of mixing in microreactors. In this paper, numerous commercially available micromixers are evaluated using the Villermaux–Dushman reaction scheme and the interaction by exchange with the mean (IEM) mixing model to quantify the mixing time. The work presents the mixing times as a function of flow rate and energy dissipation for mixers including T-mixers, Ehrfeld Mikrotechnik BTS micromixers, and Syrris Asia microchips.