Baseline maternal and pregnancy characteristics were balanced between groups. Among 354 women who presented for an enrollment visit, 98 were excluded from the trials at the study visit and included in this analysis. Of these, the majority (n¼60, 17% of all women evaluated) were excluded for ultrasound findings. In this group, 49 women (14% of all women evaluated) were excluded due to a diagnosis of fetal growth restriction (regardless of antenatal testing), and 11 (3.1% of all women evaluated) were found to have polyhydramnios. (Fig 1). CONCLUSION: As we consider implementing outpatient cervical ripening into clinical practice, appropriate identification of low-risk patients is crucial. A third trimester ultrasound prior to outpatient cervical ripening identifies findings that may influence plans for outpatient cervical ripening and should be performed as part of clinical protocols.
adjustment for vaginal bleeding, lack of prenatal care, history of multiple preterm deliveries, earliest prior delivery < 32 weeks, penultimate delivery 34 weeks, inter-pregnancy interval < 12 or 3 24 months, and surrogates for cervical shortening (vaginal progesterone and pessary) and dilation (exam-indicated cerclage), we found first recorded maternal weight < 215 lb, weight gain < 0.5 lb/ week and male fetus are associated with a higher odds of sPTB. Accounting for these factors, the odds of recurrent sPTB was lower for black women (OR 0.46, 95% CI 0.36-0.69). The bootstrapped area under the curve for the model incorporating these factors was 0.77 (95% CI 0.71-0.80). CONCLUSION: Treatment with 17-OHPc was not predictive of pregnancy prolongation in women with a history of sPTB, but we have found evidence of resilience against recurrent preterm birth among black women in our cohort.
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