The specific narcotic antagonist naloxone (0.4 milligram) was given intravenously to seven chronic schizophrenics who reported that they had very frequent auditory hallucinations. Saline solution was used as a placebo. The coded study did not reveal any effect of naloxone on hallucinations or on global psychopathology.

No abstract

Among 2201 public psychiatric patients evaluated for polydipsia (excessive ingestion of nonalcoholic beverages) there was a prevalence rate of 6.2%. Their mean age was 50.9 yr., being substantially younger than the comparable population of state patients, but predominantly chronic. Diagnoses were 73% schizophrenia, but mental retardation and alcoholism were also over-represented. Patients were predominantly white and almost 60% women. Almost one-quarter of the polydipsic patients met the diagnostic criteria for one or more instances of water intoxication.