Meeting the production demand in today's market without sacrificing performance of the artificial lift method is critical. Aggressive flowback procedures lead to solids production and unplanned electric submersible pump (ESP) shutdowns because of solids overload. A novel pump protection system has been designed, tested, and installed in the field. The system enhances the ESP life, improves restarts, and reduces downhole vibrations and unplanned shutdown by controlling the solids flowback and sending solids-buildup pressure signals. A comparative study on three ESP wells in the Delaware basin (US) demonstrated the efficacy of the system. The system comprises of an intake sand control screen and valve assembly. The novel stainless steel wool screen acts as a three dimensional (3D) filter capable of filtering out particles of 15 to 600 μm, and the valve assembly activated by differential pressure across the screen creates a secondary flow path to allow cyclic cleanup of the screen. Stainless steel wool screen with variable pore sizes is used as the sand control media for its high efficiency in preventing the flow of most of the solid particles. When the solids build up on the screen surface, the valve assembly opens upon reaching a preset differential pressure to enable flow past the screens and into the ESP and allows sands deposited on the screen surface to fall off. The pump protection assembly was tested at surface and installed in three wells along with downhole ESP gauges measuring pressure, temperature and vibrations after pulling out existing ESP completions. Qualification testing confirmed the opening of the valve assembly after solids buildup on the stainless steel wool screen. It also validated that the deposited sand fell-off from the screen surface after flow diverted through the valve assembly and pressure differential across screen dropped. In the field installations, the run life of the ESPs improved by an average of 35%, with comparable production volumes and slow drawdowns. In addition, the number of ESP shutdowns related to sand and solids was reduced by as much as 75%, improving longevity of electrical components. The success rate of ESP startups after planned and unplanned shutdowns also improved by 22%. The increase in inlet pressure captured via the downhole gauges when the valve assembly opened indicated the sand control prevention and mitigation system was bridged, and ESP replacement should be scheduled to minimize deferred production from a solids-induced ESP failure and to minimize surface solids management costs. The vibration signal data obtained from downhole sensors confirmed the reliability of the system. Overall, results demonstrate that the system designed is successful at increasing ESP run life without detriment to well production performance. The new, field-proven pump protection system along with its components and the completion design substantially increase life of ESP by reducing the number of shutdowns related to sand overload, reducing shutdowns, reducing overall vibrations, increasing the probability of successful start after shut-in, and increasing the performance reliability during fracturing of a neighboring well. Consequently, more wells that are looking to increase the ESP life can now benefit from this technology and increase output.