Development of epithelial malignancies leads to well documented molecular and structural changes in the epithelium. Recently, it has been recognized that stromal biology is also altered significantly with preinvasive disease. Oral Squamous Cell Carcinoma comprises a bulk of all oral malignancies. In Oral Squamous Cell Carcinoma, cell invade the stroma in the form of islands, strands or sheets, which are embedded or surrounded by an extracellular matrix, thus producing reactive changes in the stroma. Reticulin fibers along with collagen fibers, is not only responsible for maintaining the functional integrity of tissues but is also thought to play an important role in pathogenesis and invasion in Oral Squamous Cell Carcinoma. In this study, reticulin fibers were studied histopathologically for the length, thickness, density of colour and uniformity of stain of in various grades of Oral Squamous Cell Carcinoma with Gomari silver reticulin stain. Thus, the present study helps in documentation of connective tissue changes in various grades of Oral Squamous Cell Carcinoma .

This report describes management of furcal perforation in mandibular first molar by bicuspidization and regeneration of bone using an osseograft. 45 years male individual was reported having inflammation in the right mandibular posterior region of the jaw with periodic exacerbation and remission. On examination, sinus opening was found in relation to buccal side of 46. Radiographic examination revealed radiolucency and radio-opaque mass in the furcation area of 46 suggestive of foreign body. The patient was diagnosed of primary endodontic involvement with secondary periodontal lesion of tooth 46. Antibiotic coverage followed by abscess drainage of 46 was done. Surgical procedure was scheduled with bicuspidizaton technique and bone grafting. After the thorough debridement, the furcation defect was filled with an osseograft. Subsequently, 6 week later, toot preparation for porcelain fused to metal restorations was performed on dissected portions. Post operatively, the patient follow up was done at 1 st month, 2 nd month and 6 th month.

Background:The intention behind study was to scrutinize the periodontal status of patients with metabolic syndrome (Met.S) and periodontitis patients without Met.S and relate to general healthy subjects, to define whether the periodontal status was consistent in patients of Met.S.Methods: A total of 150 subjects were scrutinized during study. Group one consisted of 50 healthy controls, group two consisted of 50 chronic periodontitis patients and group three consisted of 50 subjects with confirmed Met.S. Gingival Index, Bleeding Index (Ainamo & Bay), Probing Pocket Depth (PPD), Clinical Attachment Level (CAL), were noted. Medical examination and blood investigations included measurement of Body-Mass Index (BMI), serum lipid profile, fasting blood glucose and blood pressure. Metabolic syndrome was defined according to NCEP ATP III definition. The results obtained were analyzed statistically using SPSS output. Results:The results of the present study showed that the periodontal condition of group three patients were poor compared to group one &two patients. The periodontal conditioned worsened in patients of metabolic syndrome. Conclusion:Based on the results of our study, it can be concluded that periodontitis and metabolic syndrome were confounding the systemic effects of each other. Dentists should counsel their patients regarding the health hazards of metabolic syndrome and periodontitis and motivate them to maintain good oral hygiene and follow healthy life-style.

Oral cavity is said to be the mirror of systemic health. Many systemic diseases first manifest in the oral cavity. Also an oral disease has a potential to act as an independent risk factor for causing systemic disease. This bidirectional view is gaining acceptance currently, due to findings that, association between periodontal disease and systemic conditions such as Metabolic Syndrome. Effort has brought advances in revealing the etiological and pathological links between the chronic inflammatory dental disease, periodontitis and systemic condition, Metabolic Syndrome. The role of microorganisms in periodontal disease is well documented. In the last 10 years, studies have been published indicating a positive or negative relationship between periodontitis and various systemic diseases, including Met.S. The most frequently isolated microaerophilic pathogens are (A.actinomyctemcomitans, Campylobacter rectus, and Eikenellacorrodens) and anaerobic pathogens are (P.gingivalis, Bacteroidesforsythus, T.denticola, Prevotella intermedia, Fusobacterium nucleatum, Eubacterium, and spirochetes). In the present study P.gingivalis periodontal pathogen confirmed increased colonization of periodontal pathogens, are cultured in both periodontitis patients without Met.S and Periodontitis patients with Met.S.

Oral cavity is said to be the mirror of systemic health. Many systemic diseases first manifest in the oral cavity. Also, an oral disease has a potential to act as an independent risk factor for causing systemic disease. This bidirectional view is gaining acceptance currently, due to findings that, association between periodontal disease and systemic conditions such as Metabolic Syndrome. Effort has brought advances in revealing the etiological and pathological links between the chronic inflammatory dental disease, periodontitis and systemic condition, Metabolic Syndrome. The role of microorganisms in periodontal disease is well documented. In the last 10 years, studies have been published indicating a positive or negative relationship between periodontitis and various systemic diseases, including Met.S. The most frequently isolated microaerophilic pathogens are (A.actinomyctemcomitans, Campylobacter rectus, and Eikenellacorrodens) and anaerobic pathogens are (P.gingivalis, Bacteroidesforsythus, T.denticola, Prevotella intermedia, Fusobacterium nucleatum, Eubacterium, and spirochetes). In the present study P. gingivalis periodontal pathogen confirmed increased colonization of periodontal pathogens, are cultured in both periodontitis patients without Met.S and Periodontitis patients with Met.S.