Introduction: Severe acute respiratory syndrome coronavirus 2 causing coronavirus disease 2019 (COVID-19) pandemic have spurted in three major waves in India at different times and had different levels of severity in different waves. The objective of our study was to determine the comparative mortality rate in three COVID-19 waves and determine the factors associated with mortality. Methods: We identified a cohort of 1,132 COVID-19 patients who were admitted between April 14, 2020 and February 08, 2022 at our center. All the admitted patients with positive COVID–polymerase chain reaction were included in the study. Sample characteristics were determined by screening age, sex, socio-economic status, occupation, symptomatology of COVID, patient status on admission, baseline investigations, comorbidities, medical history, oxygen dosage needed during admission, the span of hospital stay, diagnosis, and vitals such as blood pressure, pulse, and oxygen saturation. All the data were procured from an institutional database. Results: In total, 1,132 patients included in the study, the mean age was 65.08 ± 12.29 and 56% were males. The affliction rate was 42.13% in >60 years, 29.5% in 46-60 years, 20.8% in 31-45 years, and 7.4% in 30 years’ group. In the first, second, and third waves of COVID-19, the mortality rates were 13.21%, 23.53%, and 11.39%, respectively. Among the comorbidities, mortality rates were proportionately higher in those with hypertension (6.7%), and diabetes (5.5%), than those with chronic obstructive pulmonary disease (3.3%), chronic kidney disease (CKD) (1.5%), heart disease (1.6%), and malignancy (0.2%). Conclusion: We identify the peaked mortalities in the second encounter which was predicted by age, comorbidities such as hypertension, and diabetes.

Background: Uterine leiomyoma (i.e. fibroid or myoma) are benign clonal tumours arising from the muscle cell of the uterus .Uterine myomas are the commonest tumour over the age of 30 years and seen in 2% pregnant women. The impact of uterine myomas on pregnancy depends on the size, number and location of myoma. Myomectomy is a surgery to remove one or more fibroids. Recently, it has been suggested that caesarean myomectomy is a safe surgical modality if is performed in carefully selected patients. The aim of the study was to assess the safety and feasibility of performing myomectomy during caesarean section.Methods: This prospective observational study was conducted in the Postgraduate Department of Gynaecology and Obstetrics for a period of one and a half year in Government Lalla Ded Hospital – an associated hospital of Government Medical College, Srinagar which is the sole tertiary care referral centre in the valley.Results: A total of 54 patients were taken for caesarean myomectomy. Majority of the patients were in the age group of 26-30years and were of para-1 or 2. Mean blood loss was ≤500 ml during surgery. Most common intraoperative complication was haemorrhage and post-operative complication was fever.Conclusions: From the present study, it is concluded that with the advent of better anaesthesia and availability of blood, caesarean myomectomy is no longer a dreaded job in the hands of an experienced surgeon and in a well-equipped tertiary institution.