ÖZET Anahtar sözcükler: anti-tüberküloz ilaçlar, BACTEC MGIT 960 sistemi, direnç, Mycobacterium tuberculosis kompleks SUMMARY Resistance Ratios of Mycobacterium tuberculosis Complex Strains Isolated in Erzurum Regional Tuberculosis Laboratory Against Major Antituberculosis Drugs Tuberculosis is an important health problem for many countries in the world, especially in the developing countries. The aim of this study is to determine resistance rates of Mycobacterium tuberculosis complex (MTC) strains isolated from various clinical specimens in our region against isoniazid (INH), rifampicin (RIF), streptomycin (SM) and ethambutol (ETM), which are primary anti-tuberculosis drugs.Between RIF and INH, was 3.33 %