Introduction. The growth of oncological morbidity and the advent of novel surgery methods to improve quality of life and longevity entail a steady growth of noncardiac surgery in elderly patients. Provided the general aging of the population, an increase in the number of comorbid patients and a growing use of medical implanted devices, the assessment of main risk factors for perioperative complications acquires a higher relevance.Materials and methods. On the basis of a clinical case of an elderly patient, approaches to perioperative risk assessment; methods for risk factor isolation during the preoperative stage; and the importance of informing the patient about the incurred risk are discussed.Results and discussion. A postmortem examination established stage IV coronary atherosclerosis of 3rd degree, stenosis of left and right coronary artery lumen to 60–80%, atherosclerotic plaque wall raptures in the left coronary artery with haemorrhage into the base (“unstable plaque”), ischemic myocardial dystrophy, pockets of abnormal myocardial blood flow. Th e conducted analysis of the clinical case, along with a review of existing literature sources and American and European guidelines for cardiac risk assessment in non-surgical patients, demonstrates the need for updating domestic recommendations on perioperative risk assessment. Such a revision should complement the current international experience with the meta-analysis of the prognostic value of stress tests, routine coronary angiography and preventive pre-surgical coronary recanalisation.Conclusion. It can be concluded that the existing clinical recommendations and risk assessment scales fail to provide immediate solutions to ensure sufficient patient’s safety in the operating room; rather, these documents should only be considered as a vector for decision making in particular clinical circumstances.

This article analyzes the relationship and influence of factors such as the population, the level of motorization, economic development, and the state of the state road network on the state of the risk of road accidents, including the level of mortality and road injuries, as well as the relevance of improving methods for assessing, managing and predicting the risk of accidents in road traffic. National indicators of the level of road deaths and injuries in different countries were studied. The relationship between road accidents and the level of motorization, income of the population, the state of the road network, and other indicators were revealed. The urgency of the problem of road accidents and the organization of measures to reduce the level of road accidents is emphasized. It also takes into account the special importance of forming conceptually new approaches to the task of improving the efficiency of public administration in the field of organization and maintenance of road traffic through the implementation of the Concept of Road Safety in the Republic of Uzbekistan for the period 2018-2022, which includes the following main directions: further improvement of the regulatory framework in the field of road safety, including significant strengthening of responsibility for gross violations of traffic rules; comprehensive improvement of road infrastructure, improving the quality of roads, creating reliable conditions for the safe movement of vehicles; improving the legal culture, the necessary knowledge, and skills of road users, strengthening their discipline.

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