BACKGROUND The control of hemodynamic status is important because it can affect intraocular pressure (IOP) in patients undergoing eye surgery. We wanted to compare IOP changes in patients undergoing cataract surgery based on local anaesthesia and general anaesthesia with laryngeal mask and laryngoscopy types. METHODS In this double-blind non-randomized controlled trial; 170 patients 40-80 years old (ASA class I-II) candidates for elective cataract surgery enrolled to the study by convenience sampling method. After informed consent, patients were allocated to five groups A, B, C, D and E respectively. A) local anaesthesia, B) Macintosh laryngoscope, C) McCoy laryngoscope, D) video GlideScope and E) laryngeal mask airway. Systolic and diastolic blood pressures, mean arterial pressure, oxygen saturation and IOP were measured before, immediately and 5 minutes after airway intervention. IOP was measured with a Tono-Pen. Data was analysed by SPSS-16 using repeated measure ANOVA (Analysis of Variances), post hoc Tukey and chi-square tests. p-Value less than 0.05 was considered statistically significant. RESULTS 115 patients (67.6%) were female and 55 (32.4%) were male. In the local anaesthetic group, mean of IOP decreased significantly after airway intervention (p= 0.001). In laryngeal mask, Macintosh laryngoscope, McCoy laryngoscope and video GlideScope groups, IOP increased immediately and decreased 5 minutes after airway intervention (p = 0.001). Before the airway intervention, the mean of IOP in local anaesthetic group was higher than other groups (p= 0.012). Immediately and 5 minutes after air intervention, mean of IOP of the Macintosh laryngoscope was higher than other groups respectively (p< 0.001, p= 0.029). CONCLUSIONS Our results showed that Macintosh laryngoscopy has more effects on IOP in patients undergoing cataract surgery in comparison to other anaesthetic methods. HOW TO CITE THIS ARTICLE: Domari AA, Sarkoohi A, Taghavi Y, et al. Comparison of intraocular pressure changes in patients undergoing cataract surgery, based on local and general anaesthesia with laryngeal mask airway and laryngoscopy types. J.