Our study aimed to estimate visfatin hormone levels and lipid profile levels in some patients. The study group included 20 women with breast cancer and a control group of 10 healthy women. The hormonal and biochemical assays include visfatin hormone, total cholesterol (TC), TGS, LDL-C, HDL-C, and VLVL-C. The results showed a significant increase at (P≥0.05) in visfatin, TC, TGS, LDL-C, and VLDL-C in breast cancer patients compared to the control group, while HDL-C didn't show any significant difference between both groups.