Purpose: To study the pattern electroretinogram changes in primary open-angle glaucoma patients in correlation with visual field changes and optical coherence tomography measurements of retinal nerve fiber layer thickness in the peripapillary region in an attempt to evaluate the clinical value of pattern electroretinogram as an objective test of functional deficit in glaucoma. Patients and Methods: The study included 81 eyes of 81 participants: 50 primary open-angle glaucoma patients, 16 primary open-angle glaucoma suspects, and 15 controls. All subjects underwent visual field testing using 24-2 Humphrey standard automated perimetry, peripapillary retinal nerve fiber layer average thickness using the 3.4-mm circular scan of the Heidelberg OCT spectralis and pattern electroretinogram using CSO RetiMax device in accordance with the International Society for Clinical Electrophysiology of Vision guidelines. Results: We had three main groups: normal, glaucoma suspect, and primary open-angle glaucoma patients, and the last group included three subgroups: mild, moderate, and severe. There was significant difference in the visual field mean deviation, peripapillary retinal nerve fiber layer average thickness, and most pattern electroretinogram measured parameters between the three main groups and in between primary open-angle glaucoma subgroups. There was significant positive correlation between visual field mean deviation and the peripapillary retinal nerve fiber layer average thickness, P50 amplitude, and P50–N95 amplitude (p < 0.001, p = 0.018, and p < 0.001, respectively). Significant negative correlation was also found between peripapillary retinal nerve fiber layer average thickness and N95 amplitude (p < 0.001). Significant positive correlation was found between retinal nerve fiber layer average thickness and P50–N95 amplitude (p = 0.001). Significant negative correlation was found between peripapillary retinal nerve fiber layer average thickness and N95 amplitude (p = 0.001) and significant positive correlation of retinal nerve fiber layer average thickness with P50–N95 amplitude (p = 0.017) in primary open-angle glaucoma patients. Conclusion: Peripapillary retinal nerve fiber layer average thickness shows significant negative correlation with pattern electroretinogram N95 amplitude and a significant positive correlation with P50–N95 amplitude. In combination with optical coherence tomography, pattern electroretinogram can be used to objectively assess functional loss in glaucoma.

Purpose: To describe technique and evaluate outcomes of using amniotic membrane onlay strip for repair of corneal lacerations.Methods: Retrospective case series included eight eyes with traumatic corneal lacerations. A strip of amniotic membrane was applied to the corneal surface to cover the wound. Wound was then sutured with nylon 10/0 sutures involving the membrane. Sutures were well-spaced and suturing was avoided in the visual axis. Average keratometric reading (average K), keratometric astigmatism (KA), manifest refractive astigmatism (RA) in diopters (D) and spectacle or soft contact lens best corrected visual acuity (BCVA) were assessed 2 months after suture removal. Results: Transient postoperative hypotony was encountered in five cases (62.5%). Average K was 44.61 ± 2.81 D (mean± SD). KA was 2.20±0.71 D (mean± SD). RA was 1.78 ± 0.73 D (mean± SD) and ranged from 1 to 3 D. Log MAR BCVA was 0.39±0.18 (mean± SD) ranged from 0.22 to 0.70.Conclusions: The application of amniotic membrane onlay strip during repair of corneal lacerations was associated with good visual outcome possibly due to reduction of wound and suture related corneal astigmatism.

Background: To describe technique and evaluate outcomes of using amniotic membrane onlay strip for repair of corneal lacerations.Methods: Retrospective case series included eight eyes with traumatic corneal lacerations. A strip of amniotic membrane was applied to the corneal surface to cover the wound. Wound was then sutured with nylon 10/0 sutures involving the membrane. Sutures were well-spaced and suturing was avoided in the visual axis. Average keratometric reading (average K), keratometric astigmatism (KA), manifest refractive astigmatism (RA) in diopters (D) and spectacle or soft contact lens best corrected visual acuity (BCVA) were assessed 2 months after suture removal. Results: Transient postoperative hypotony was encountered in five cases (62.5%). Average K was 44.61 ± 2.81 D (mean± SD). KA was 2.20±0.71 D (mean± SD). RA was 1.78 ± 0.73 D (mean± SD) and ranged from 1 to 3 D. Log MAR BCVA was 0.39±0.18 (mean± SD) ranged from 0.22 to 0.70.Conclusions: The application of amniotic membrane onlay strip during repair of corneal lacerations was associated with good visual outcome possibly due to reduction of wound and suture related corneal astigmatism.