Multidrug resistance is a global healthcare problem. Gram-negative organisms, particularly Enterobacteriaceae strains are responsible for almost 60% of nosocomial infections. Colistin acts as the last treatment resort in complicated, critical, and MDR cases; also become resistant in the last few years in an escalating manner. Its resistance has been reported almost all over the world. Since there is no alternative antibiotic of colistin-resistant isolates is available. The last year of 2020 was completely engaged with the Covid-19 pandemic for global healthcare systems. This issue is still persisting with no solution. Strict infection control policies and a noval antibiotic with lesser side effects are great in demand to resolve this issue. We gathered 28 studies from 2010 that reported colistin resistance among Enterobacteriaceae throughout the world. Colistin resistance still reported and escalated globally with no available solution. Asia was the leading region with 50% of selected studies followed by Europe and Klebsiella pneumonia and Klebsiella species were the leading organisms of colistin resistance among Enterobacteriaceae. This mini-review was designed to highlight the global importance of colistin-resistant isolates among Enterobacteriaceae, which still an unanswered question.

The incidence of meniscal tear injuries is rising, predominately due to the sporting activities of young adults. There are different methods in orthopedics of meniscal tear management. An Arthroscopic Partial Meniscectomy (APM) is the most practiced orthopedic procedure globally. However, recent literature reported serious concerns about its positive outcome. Meniscal repair is another recommended technique and growing rapidly due to its less incision requirement. Partial Meniscal implant is a modern management strategy with the excellent outcomes but still required further large-scale research. Concluding to the modern strategies of meniscus tear management “Save the meniscus!” is the emerging approach. This review critically analyzed the most adapted management strategies of meniscal tear and the emerging ones.

Total Laboratory Automation (TLA) is the future of laboratory diagnostics due to its efficiency, reproducibility, better turnaround time (TATs), precision, sensitivity, and specificity. Microbiology is generally considered a human dependent field and still, most of the microbiology world is confused with TLA implementation. Two better-claimed technologies BD Kiestra InoqulA and Copan WASP have emerged as a well satisfactory solution of microbiology automation in the last decade. Here we design a practical approach and reviewed all studies of BD Kiestra InoqulA and Copan WASP, assessed microbiology samples in a healthcare setting.

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Background: The global COVID-19 spread is unquestionably one of the leading obstacles of every healthcare system, patient, and healthcare professionals. This leading pandemic has immeasurable effects on every healthcare domain, including surgical care, especially surgical demand for emergency settings. Methods: An extensive data search was done from two leading databases Medline (PubMed) and Google Scholar, by using different keywords. The literature search was done both using individual and combination of keywords. All relevant data published from December 2019 to April 2021 were included and narratively analyzed. Results: Thirteen articles were selected based on COVID-19 and its consequences on emergency Surgical Services including recommendations, guidelines, prioritization, and reporting of surgical case reduction. Conclusion: This global COVID-19 pandemic had influenced all domains of surgery, including emergency surgery, which required urgent surgical attention. Training and multidisciplinary support are necessary for the surgical teams to perform in this critical situation.