The present study was carried out for evaluating the response of chickens from four genotypes such as naked-neck, frizzle, normal feather and broiler subject to heat stress in order to show the best bird genotype. Thus, for achieving that purpose, the study was conducted in a private farm located in the locality of Tiéplé, precisely in the center of Côte d'Ivoire in the department of Bouaké. The experimental chickens were selected randomly from a group of chickens genotypes identified and were exposed to ambient temperature and warm temperature. Results showed that temperature had a significant effect onto breath rates of broiler and frizzle genotypes, but it had no significant effect on that of the normal and naked-neck genotypes. Moreover, temperature influences significantly the white blood cell and hemoglobin rates of all genotypes (p <0.05) which increase according temperature level. Likewise, a significant effect of temperature onto the MCHC rates of all bird genotypes was observed (p ˂0.05). This rate increases with increasing of heat stress for all genotypes. However, there is no significant effect of temperature on the calcium and phosphorus rates of all genotypes (p˃0.05). Otherwise, temperature does not have any effect on magnesium rate of the naked-neck and broiler genotypes, (p> 0.05), while it influences significantly the magnesium rates of normal feathered birds (p ˂0.05). The results of this work indicated therefore that there was a relationship between heat resistance or tolerance and acclimation of birds which it is in favor to indigenous chicken genotype precisely the naked-neck genotype.