No abstract

No abstract

In the present work a novel potentiometric sensor, based on a noncovalent imprinted polymer, was developed for determination of Lamotrigine (LTG). At optimized conditions the electrode exhibited a Nernstian response (30.8 AE 1.0 mV decade À1 ) in a concentration range of 1 10 À6 to 1 10 À3 M with a detection limit of 8 10 À7 mol L À1. The potential response of the electrode was constant in the pH range of 1.0-5.0. The electrode demonstrated a response time of~30 s. The selectivity coefficient of the sensor toward a number of different drugs with molecular similarities and some metal ions was evaluated. The electrode was examined for determination of LTG in real samples.

A novel carbon paste ion selective electrode for determination of trace amount of lutetium was prepared. Modified (functionalized) multiwalled carbon nanotubes (f‐MWCNTs) were used for improvement of a lutetium carbon paste sensor response. MWCNTs have a good conductivity which helps the transduction of the signal in carbon paste electrode. In this work it is shown that introducing certain functional groups on MWCNTs can improve the electrode signals. The electrode composition of 20 % paraffin oil, 56 % graphite powder, 18 % ionophore and 6 % f‐MWCNTs showed the stable potential response to Lu3+ ions with the Nernstian slope of 21.1 (±0.3) mV decade−1 over a wide linear concentration range of 1.0×10−6–1.0×10−1 mol L−1. The electrode has fast response time (<15 s) and long term stability (about one month).

No abstract