Ondansetron was effective in reducing the incidence of nausea and vomiting in patients receiving intrathecal morphine for Caesarean section.

We conducted a prospective, randomized, double-blind clinical trial comparing droperidol 1.25 mg intravenously (i.v.) (group 1, n = 30), ondansetron 4 mg i.v. (group 2, n = 30), or both (group 3, n = 30) in the prevention of postoperative nausea and vomiting (PONV) in the first 24 h following major gynaecological procedures under combined general and epidural anaesthesia. PONV was analysed by a linear nausea/vomiting score, incidence of nausea and vomiting, and the need for antiemetic rescue. Our results showed a similar incidence of nausea and vomiting in all groups (G1 33%, G2 40%, G3 43%). However, when comparisons were made according to the time of assessment, combination therapy resulted in significantly lower PONV than droperidol in the first hour (0% vs. 13%, P < 0.05) and second hour (0% vs. 13%, P < 0.05), and than ondansetron on the first hour (0% vs. 13%, P < 0.05). A trend persisted up to the fourth hour but was not statistically significant in either group. In conclusion, droperidol and ondansetron are effective agents in the prevention of PONV, and their combination seems to provide slightly better results than either drug alone.

No abstract

Este trabalho apresenta características e resultados de ensaios realizados em implantes e componentes, com conexão cônica interna. Nele, estão descritas as características principais do sistema: suas diferenças com relação ao sistema convencional e informações relativas ao conceito do produto. Foi usado o método de elementos finitos, como ferramenta de validação de projeto, juntamente com ensaios experimentais. A superfície dos implantes foi caracterizada através de microscopia eletrônica. Palavras-chave: Implantes Dentários; Cone Morse; Superfície Tratada; Resistência de Implantes.