The possibilities of using locally available two Iraqi clays kaolin and attapulgite are have been investigated for adsorption of model drug solution of enalapril maleate. U.V. spectrophotometric technique has been utilized to produce quantitative adsorption data at different temperatures. The effect of acidity on the quantity adsorbed of this drug was investigated at Ph = 1.2 in an attempt to simulate the acidity of gastric fluid and at neutral pH. The possible effect of ionic strength on the amount of drug being adsorbed was studied using normal saline at different concentrations. The equilibrium adsorption contact times were determined for both two adsorbents used adsorption isotherms have been analyzed by the Freundlich and Langmuir models. The results of these studies demonstrated that enalapril maleate is adsorbed by both kaolin and attapuligate surfaces, and these two surfaces can be used as a physical antidotes against poisoning by the above drug overdose in vitro.
In this study, removal of one of antibiotic drags from aqueous solution by adsorption was investigated. For this purpose, trimethoprim was used as one of antibiotic drug model. The cellulose acetate polymer and attapuligate clay were used as adsorbents. The equilibrium adsorption contact time were investigated for both cellulose acetate and attapuligate. Adsorption isotherms of trimethoprim on the two surfaces used from aqueous solution were determined. These adsorption isotherms were seen to be consistent with Freundlich adsorption isotherm. k and n constants were determined from Freundlich linear equation. The effect of initial drug concentration, temperature, pH of solution, ionic strength and desorption of the drug from the two adsorbents were studied.
In this work, the adsorption of DB2 dye on yttrium oxide (Y2O3) nanoparticles was investigated under various experimental conditions. The effect of temperatures and pH were studied, it was noted that the increasing in temperatures increases the adsorption quantity, which is increased in icidic medium and decreased in basic medium. The isotherm models ( Langmiur, Freundlich, Temkin, Halsey and Harkins-Jura) were applicated and the isotherms can be arrange according to its high correlation-coefficients as follows: Freundlich (0.969) > Harkins-Jura (0.957) > Halsey (0.944) > Temkin (0.942) > Langmiur (0.902), the Freundlich isotherm model is suitable for the adsorption process. Thermodynamic Parameters such as ΔH, ΔG and ΔS were calculated from the slops and intercepts of the linear variation of lnk against 1/T, where noted that the adsorption of DB2 dye on Y2O3 nanoparticles is (endothermic reaction)
In this work the photo degradation of glibinclamide is studied by UV light and different concentrations using solvents (water and ethanol) and different times. The reaction kinetic is studied and found that the photo degradation reaction of glibinclamide is (first-order) reaction and the thermodynamic properties (ΔHo, ΔSo and ΔGo) for glibinclamide were calculated and it was found to be (endothermic and spontaneous reaction).
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