Simple and Condensed β-Lactams. Part 28. Synthesis of C-Methylcarumonams and of a Related Bis(carbamate). -The title compounds (XI), which are prepared via lactams like (VI) as the key intermediates, are found to be devoid of any antibacterial activities. -(FETTER, J.; BERTHA, F.; KAJTAR-PEREDY, M.; LEMPERT, K.; SAPI, A.; J.
Simple and Condensed β-Lactams. Part 29. Synthesis and Base-Catalyzed Ring Transformation of 4-[(2RS,3SR)-3-Hydroxy-1-(4methoxyphenyl)-4-oxoazetidin-2-yl] thiazol-2(3H)-one.-The azetidinylthiazolone (XII) is rearranged into the thiazolopyrazine derivative (XIII) on treatment with Na 2 CO 3 under mild conditions. In contrast, the chlorophenoxy derivative (XIV) is stable under the same conditions.-(SAPI, A.; FETTER, J.; LEMPERT, K.; KAJTAR-PEREDY, M.; CZIRA, G.; Tetrahedron 53 (1997) 37, 12729-12738; Dep. Org. Chem., Tech. Univ. Budapest, H-1521 Budapest, Hung.; EN)
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