Alizarin-phenylboronic acid interactions were used in a new design strategy for self-organized fluorescent sensors of metal ions and anions. First, Alizarin Red S (ARS), which binds effectively to phenylboronic acid (PBA) at neutral conditions in water, proved to be an excellent fluorescent indicator for the selective detection of metal ions; the fluorescent-active ARS-PBA ensemble causes an efficient and selective quenching in the fluorescence by adding metal ions. It was also found that anion-induced phenylboronates can bind effectively to alizarin and greatly enhance the fluorescence in MeOH. The observation makes it possible to design new self-organized anion sensory systems composed of alizarin (as reporter) and phenylboronic acids (PBAs, as receptor), such as PBA or 3-nitrophenylboronic acid (NPBA). By combining spectroscopic studies (UV-vis and fluorescence) and 11 B NMR measurements, a ternary complex (F 2 -alizarin-PBAs) has been determined. The resulting self-organized sensory system is applicable even to the detection of anions dissolved in water, when liquid [alizarin, PBA, 18-crown-6 in CH 2 ClCH 2 Cl]-liquid [KX (X 5 halogen, OAc, H 2 PO 4 ) in water at pH 5.5] two-phase extraction is employed.

A 67-year-old man developed an acute myocardial infarction shortly after normal exercise testing. His clinical history and findings from emergency coronary arteriography suggested that coronary artery spasm followed by intraluminal thrombosis might have been responsible for the myocardial infarction. Although intracoronary thrombolysis two hours after the onset of chest pain provided continued patency of an occluded vessel, serial myocardial perfusion scintigraphies documented myocardial injury, which was probably induced by reperfusion, rather than myocardial salvage.

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Abstract. Carcasses of 22 species of migrant birds were observed at the alpine area of Mt. Norikura in early spring late April to middle May . These migrants died by snowstorms that they encountered during spring migration when they passed over the alpine area.