A modified version of the IMPACT heteronuclear multiple bond correlation (HMBC) has allowed the characterization of an organosilane and a tetrasilylated yttrium complex. With the help of this sequence, an average gain in sensitivity close to 2 has been obtained compared with the standard HMBC experiment for disilanes as well as for yttrium complexes containing silylated ligands. This modified version of this long-range correlation experiment opens the way for following kinetics in the range of a fraction of a minute and to study by NMR low concentrated samples and low abundant nuclei.

This feature focuses on a reagent chosen by a postgraduate, highlighting the uses and preparation of the reagent in current research Spotlight HexamethyldisilaneCompiled by Audrey Giros Audrey Giros was born in 1984 in Conflans Ste Honorine, France. She graduated from the National Polytechnic School of Chemical Engineering and Technology of Toulouse in 2009 and received in the same year her M.Sc. degree in organic chemistry. She is currently working under the supervision of Dr. Luis Blanco and Dr. Sandrine Deloisy. Her Ph.D. research project focuses on organosilicon chemistry for the total synthesis of a sila-analogue of testosterone. She is developing methodologies for the synthesis of a siliconsilicon bond-containing molecules and their use in various reactions such as functionalization or cyclization.