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Background: Inflammation in the arterial intima has the main role for the pathogenesis of atherosclerosis. Objective: To determine the correlation between serum hsCRP levels and severity of coronary artery disease in a sample of patients referring to Surgical specialty Hospital-Cardiac center in Erbil City 2018. Patients and Methods: In this cross sectional study 120 patients (78 male and 42 female patients) were studied who had undergone coronary angiography procedure among them 80 patients (57 male and 23 female) had Coronary artery disease and the remain 40 patients had normal coronary angiography result. The blood samples from (120) patients were taken and transferred to the laboratory after clotting hsCRP was measured using cobas automated assay. Results: Here we detected a significant difference in the level of hsCRP between patients with coronary artery diseases and patients with normal coronary artery on angiography in addition to that fact the association for the severity of coronary artery disease and hsCRP level between single, two vessels and three vessels diseases, was statistically significant as well a finding which was comparable with other studies that detected a significant difference between hsCRP among patients with more severe coronary artery lesions. Conclusion: The study concluded that high level of hsCRP is a predictor of atherosclerosis and is wise to be done for patients as a risk factor and it is not only a predictor of coronary artery disease but it predicts it is severity as well.

Back ground: Helicobacter pylori are bacteria colonize in the human epithelial cells of the gastrointestinal tract. Its infection causes different diseases, including chronic gastritis, peptic ulcers, gastric lymphoma and adenocarcinoma. H. pylori have many virulence factors attributing in one or more biological functions. Objective: Detecting the prevalence of virulence factor genes vacA, cagA, iceA among strain of H. pylori using molecular technique (PCR). Materials and methods: Sixty patients (27 male and 33 female), aged 18 and above included in the present study who showed signs and symptoms of H. pylori, and undergo endoscopy between period of November 2019 and February 2020. RUT and PCR test done to detect the presence of H. pylori infection, also PCR used to detect the three virulence factors. Results: Result showed that 44 patients, 21 (47.7%) male and 23 (52.3%) female were detected as positive H. pylori infections, among them 13 (29.5%) above 50 years, and 31 (70.4%) were below 50 years. While prevalence of the virulence factors vacA, cagA, and iceA were (100%), (84.1%), and (34.1%) respectively. Conclusion: It can be concluded that the frequency and prevalence of these genes are differed and showed significant differences among them. Also, PCR test is sensitive and accurate for detection of H. pylori virulence genes.