Introduction. Hypertrophic cardiomyopathy is an autosomal dominant genetic disease. The signs and symptoms of disease vary in terms of history and clinical course, ranging from the development of acute heart failure or even sudden death, while other patients may remain asymptomatic throughout life. At the same time, there is a lack of correlation between the genotype and the phenotype of the disease. Thus, within a family, of two members carrying the same genetic abnormality, one may present a clinical manifestation of severe heart failure, the other remaining asymptomatic. Clinical case presentation. In this paper, we report a case of a 34-year-old male who comes to see a cardiologist with complaints of moderate-intensity dyspnea, general weakness, and fatigue installed during the post-COVID-19 recovery period. Management and results. The evolutionary positive dynamics of the disease on the prescribed treatment is followed, as well as the diagnostic criteria for hypertrophic cardiomyopathy. Discussion. The discussed clinical case of acute cardiac failure in adult otherwise healthy mail is of interest because it rises clinical combinations that were not debated previously: primary diagnosed hypertrophic cardiomyopathy combined with COVID-19, post-COVID-19 isolated myocarditis, hypertrophic cardiomyopathy associated with myocarditis and infection COVID-19. If the suspicion of hypertrophic cardiomyopathy is confirmed, the eventual perianesthetic management of such a patient will change radically. The article presents details of the pathophysiology of hypertrophic cardiomyopathy and key elements for maintaining hemodynamic goals
Patologiile cardiovasculare reprezintă un subiect pe larg discutat în secolul 21. Totuși, în urma multiplelor studii efectuate asupra cardiomiopatiei hipertrofice (CMPH), unele aspecte, în special ce țin de tratament au rămas neelucidate. Cardiomiopatia hipertrofică este definită ca „o anormalitate structurală și funcțională care nu se nu se caracterizează prin limitarea circulației coronariene sau situații anormare de încărcare a cavităților inimii” [1]. În urma analizei studiilor efectuate în America de Nord, Europa, Asia și Africa, s-a observat o mărire inexplicabilă a grosimii ventriculului stâng (VS), cu o incidență în rândul adulților de 0,02 – 0,23%, aceasta prezentând cea mai des întâlnită afecțiune cardiacă de origine genetică. Cea mai periculoasă complicație a CMPH este moartea subită cardiacă (MSC), aceasta fiind și cauza principală de MSC în cadrul persoanelor de vârstă tânără. Actualmente există mai multe metode de tratament, însă nu este stabilit care este cea mai eficientă, luând în calcul multitudinea de aspecte ale bolii [1,2,3].
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