In this article, Austin Walker discusses streaming, the practice of broadcasting the gameplay footage. Providing a brief analysis of the range of streaming practices, Walker argues that streaming represents a sea change in how players share and collaborate, adding new sorts of social interactivity to an experience that was, for so long, solitary. Live streaming’s novelty grants it special status as a practice still in formation, making it especially useful in analyzing how late capitalism identifies and appropriates fresh cultural activity--doing so in this case through the development of an infrastructure that supports and encourages voluntary self-surveillance. While there are resistive elements of live-streaming, such as allowing new voices access to broadcast capabilities, streaming also represents socialized labour. Walker separates streaming into two stances: the active streaming posture, where streamers voluntarily choose to broadcast their play, and the passive streaming posture, where streaming is automatically incorporated into the hardware and/or software of the gaming platform and players are unable to opt in or out.
Background
Partial trisomy of the long arm of chromosome 11 is a rare cytogenetic abnormality. It has been characterized by variable sized duplications that lead to a range of phenotypes including growth retardation, developmental delay/intellectual disability, and distinctive craniofacial abnormalities. Congenital heart defects, skeletal abnormalities, urogenital anomalies, and hypotonia are found in some affected individuals.
Methods
We describe a 16-year-old patient presented with most of the hallmark phenotypes of trisomy 11q syndrome as well as exhibiting symptoms of hearing loss, seizures, and abnormal endocrinological and ophthalmological findings. Routine chromosome analysis and subsequent chromosomal microarray analysis (CMA) were performed to detect genetic abnormalities in this patient.
Results
We identified an abnormal male karyotype with a derivative chromosome 4 due to an unbalanced translocation between chromosomes 4 and chromosome 11. The CMA results revealed a 56 Mb duplication of chromosome 11q14.1-qter and a 874 Kb terminal deletion of the short arm of chromosome 4.
Conclusion
A genomic imbalance resulting in partial trisomy 11q was found in a patient with multiple congenital anomalies. We compared the phenotypes of all known “pure” trisomy 11q cases in the literature and find that trisomy 11q23-qter is both recurrent and the most common cytogenetic abnormality found in the reported cases. It is associated with the core features of trisomy 11q syndrome.
Graphical abstract
Preoperative ultrasound‐guided lateral abdominal wall botulinum toxin injection is a promising method for improving patient outcomes and reducing recurrence rates after ventral hernia repair. A review of the literature demonstrates variability in the procedural technique, without current standardization of protocols. As radiologists may be increasingly asked to perform ultrasound‐guided botulinum toxin injections of the lateral abdominal wall, familiarity with the procedure and current literature is necessary.
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