Abstract. Fourteen recombinant inbred lines (RIL's) obtained from IR 30 and Basmati 370 were evaluated along with two popular varieties viz. Khitish (IET4094) and Minikit (IET 4786) for 14 biometrical characters during summer 2012 at Regional Research Station, New alluvial Zone, Chakadaha, Nadia, Bidhan Chandra KrishiVishwavidyalaya, Mohanpur, West Bengal, India., in Randomized Block Design with two replications. Except number of primary branches per panicle, grain breadth and kernel breadth all the characters studied showed significant differences among the genotypes. Four lines (S 7 , S 10 , S 13 and S 14 ) possessed significantly higher grain yield than superior check variety. The high estimates of GCV and PCV were obtained for number of panicle per plant, grain yield per plant, floret number per panicle, number of grains per panicle and panicle weight. High heritability was observed for number of panicle per plant, kernel L/B ratio, kernel length, 1000 grain weight and grain L/B ratio. High genetic advance was observed for number of grain per panicle, floret number per panicle, grain yield per plant, number of secondary branches per panicle and 1000 grain weight respectively while lowest genetic advance was observed in kernel breadth. Genetic advance as percentage of mean was highest for number of panicle per plant followed by grain yield per plant, florets number per panicle and Kernel L/B ratio while lowest was recorded for kernel breadth. High heritability coupled with high genetic advance was obtained for number of grains per panicle, 1000 grain weight, kernel length and grain yield per plant. It indicated the predominance of additive gene action for controlling these characters. Therefore, these characters can be improved simply through selection. High heritability associated with low genetic advance was observed for panicle weight, grain length, grain L/B ratio and kernel L/B ratio. It suggested non-additive gene action for the expressions of these characters. The magnitude of genotypic correlation coefficient was in general higher than that of the corresponding phenotypic ones. Grain yield per plant was significantly positively correlated with number of panicles per plant, floret number per panicle and number of grain per panicle. The kernel length imparted the highest positive direct effect on grain yield per plant followed by number of grain per panicle, number of panicle per plant and panicle weight.

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There is a desperate requirement to identify non-invasive biomarkers which conceivably could delay development of the Alzheimer's disease. Biomarkers are a quantifiable signal of a certain biological condition. Biomarkers for Alzheimer can be recognized using Blood, Cerebrospinal fluid, Saliva, Urine sample has been an aim of numerous experimenter for several years. Aβ40, Aβ42, total tau, and p-tau in different body samples have characteristic use in AD. Assessment of CSF biomarker is helpful in the forecast the risk of progression from mild cognitive impairment to AD. This study is an outline of in progress joint efforts to set up biomarkers as a characteristic tool and carry out them in diagnostic procedures of the above-mentioned disease.

A pot culture experiment entitled "Impact of inorganic nitrogenous fertilizers and FYM combinations on plant height at various phases of rice growth and combinations on number of tillers per hill at various stages of effective tillers per hill during rice harvest (Oryza sativa L.)" was conducted at Institute of Agricultural Sciences farm, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar Odisha. on sandy loam soil during kharif 2018-2019.The experiment consisted of eight treatments viz. T1-Control, T2-50% RDF, T3-50% RDF + FYM @ 5 t ha -1 , T4-75% RDF, T5-75% RDF + FYM @ 5 t ha -1 , T6-100% RDF ( NPK 80:40:40), T7-100% RDF + FYM @ 5 t ha -1 and T8-150% RDF. The experiment was laid out in a Randomized Block Design with three replications. The results revealed that highest and significant values were recorded with respect to growth parameters i.e., plant height, number of tillers per hill, effective tillers per hill and yield attributes i.e., number of panicles per hill, panicle length, number of filled grains 1000 seed weight (test weight) in the treatment that received 100% RDF + FYM @ 5t ha -1 . Combination of FYM (5 t ha -1 ) with lower levels of RDF (50 and 75% RDF) also registered higher increase in the above parameters as compared to the application of inorganic fertilizers alone with the corresponding levels. Grain and straw yields followed the same trend as that of growth parameters and at higher levels of nitrogen in the inorganic form (150 % RDF) the values of the various parameters including grain and straw yield were significantly lower than the treatment where 100% RDF +FYM @ 5 t ha -1 was applied . . More nutrient content (N, P, K) in grain and straw was observed with the application of 100% RDF + FYM @ 5t ha -1 as compared with 100 and 150% RDF. With the combined application of 100 percent RDF as an inorganic source and 5tha -1 FYM as an organic source, improvements in physicochemical characteristics such as organic carbon, bulk density, porosity, and accessible macro nutrients (N,P,K) were found.