Background Patients with underlying heart failure (HF) in the setting of COVID-19 who require admission to the intensive care unit (ICU) might present with a unique set of challenges. This study aims to extensively describe the characteristics and outcomes of patients with HF who were admitted to ICU with COVID-19. Methods We conducted a multicenter retrospective analysis for all adult patients with HF and an objectively confirmed diagnosis of COVID-19 who were admitted to ICUs between March 1 and August 31, 2020, in Saudi Arabia. Results A total of 723 critically ill patients with COVID-19 were admitted into ICUs during the study period: 59 patients with HF and 664 patients with no HF before admission to ICU. Patients with HF had statistically significant more comorbidities, including diabetes mellitus, hypertension, dyslipidemia, atrial fibrillation, and acute coronary syndrome. Moreover, higher baseline severity scores (APACHE II & SOFA score) and nutritional risk (NUTRIC score) were observed in HF patients. Overall, patients with HF had more in-hospital and ICU deaths in comparison to patients without HF: (64.3% vs. 44.6%, P -value <0.01) and (54.5% vs. 39%, P-value = 0.02), respectively. Patients with HF had a similar incidence of thrombosis, ICU length of stay, duration of mechanical ventilation, and hospital length of stay compared to patients with no HF. Conclusion In this study, patients with HF had more in-hospital and ICU deaths than patients with no HF. Thus, history of HF could be used to help direct case management during hospitalization and possibly dictate proactive COVID-19 care.

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Despite the emergence of therapeutic advances, the morbidity and mortality still occur in the obstetric patients, although intensive care utilization by obstetric and gynecological patient, are still rare compared to the general population. Majority of obstetric patients needed the intensive care therapy compared to gynecological patients. The aim of our study was to know the indications for the intensive care admission by obstetric and gynecological patients, length of stay and outcome of these patients. Methods: We retrospectively reviewed the medical records of all obstetric and gynecological patients admitted to our Surgical and Trauma Intensive Care Units (SICU and TICU) from February 1995 to March 2005. Indication for admission, nationality, age, and length of stay in ICU, severity of disease and outcome of these patients were recorded. Data analyzed with SPSS program. Results: A total of 182 patients were admitted to the SICU of the Hamad Medical Corporation in Doha, Qatar, from the Women's Hospital. 159 (8 7 %) patients were obstetric patients and 23 (13%) patients gynecological patients, 126 (69.6%) patients were admitted post Lower Segment Caesarean Section (LSCS). The most common indication for admission was 73 (39.3%) patients obstetric hemorrhage and Disseminated Intravascular Coagulation (DIC), and then 44 (25.3%) patients of hypertensive disorder of pregnancy. The major anesthesia related indication was scoline apnea, 21 (11.6%). Total three obstetric patients died, two due to severe sepsis and multi-organ failure and one due to cerebral sinus thrombosis, giving mortality rate of 1.66%.

The problem in research is the lack of agility that students have at SSB Woner. the purpose of this study was to determine the effect of the zig zag run exercise on the agility of SSB Woner students. The population in this study were all students aged 15 years using a total sampling technique, amounting to 15 students. This type of research is, using a one-group pre-test-post-test design. From the results of this study it can be concluded that the average pre-test was 19.13 and the post-test was 17.05, based on the normality test LoMax pretest was 0.1329 <L table 0.22, and LoMax posttest was 0.1224 <L table 0.22 is said to be normal. based on statistical analysis of the t test, the difference value is 2.01 and produces a tcount of 15.461 and a ttable of 1.761. Means tcount > ttable. It can be concluded that the zigzag run exercise (X) has an influence on agility (Y) on soccer players in SSB Woner Keyword: zig zag run training, agility, soccer

Background: There is uncertainty about the appropriate dosing regimen, safety, bleeding risk, and the predisposing factors for thrombosis/bleeding risk in critically ill COVID-19 patients. Also, the available evidence is limited and depends either on observational studies or randomized trials with small sample size. Thus, the aim of the study is to determine the optimal dosing of pharmacological VTE prophylaxis in critically ill patients with COVID-19 patients.Methods: A multicenter, retrospective, cohort study conducted at two governmental tertiary hospitals in Saudi Arabia. All critically ill COVID 19 patients who received pharmacological VTE prophylaxis and were admitted to Intensive Care Units (ICUs) between March 1st, 2020 to January 31st, 2021 were included. Patients who received Standard dosing VTE prophylaxis were compared to patients who received high dosing pharmacological VTE prophylaxis.Results: A total of 758 patients were screened; 565 patients were included in the study. We matched 352 patients using propensity score matching (1:1) according to the baseline severity scores (i.e., APACHE II score, SOFA score), history of CKD, and AKI within 24 hours of ICU admission. The differences in venous thromboembolism (OR (95%CI): 0.75 (0.16–3.38), p-value = 0.70) and any case of thrombosis (OR (95%CI): 1.22 (0.52–2.86), p-value = 0.64) were not statistically significant between the two groups. In contrast, minor bleeding was associated with the use of high dosing regimen of VTE prophylaxis (OR (95%CI): 3.39 (1.08–10.61), p-value = 0.04). There was no difference in the 30-day ICU mortality nor in-hospital mortality between the two groups (OR (95%CI): 1.26 (0.77–2.05), p-value = 0.36 and OR (95%CI): 1.05 (0.66–1.68), p-value = 0.83 respectively).Conclusion: High dosing pharmacological VTE prophylaxis in critically ill COVID-19 patients was not associated with VTE, thrombosis, or mortality benefits but led to an increased risk of minor bleeding. Further randomized clinical and interventional studies are required to confirm our findings.