Background: Patients with diabetes are at risk for osteoporotic fractures. We propose to test the hypothesis that treatment of diabetes mellitus with metformin alone or in combination with insulin affects bone mineral density (BMD) in a positive way possibly via the Wnt/β-catenin pathway.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.