This study was undertaken to determine the seroprevalence, and associated risk factors, of hepatitis E virus. A total of 186 consented apparently healthy individuals were recruited. Interviewer-administered questionnaire was used to obtain the socio-demographic information from the individuals. Blood samples were collected and analyzed for anti-HEV using third generation enzyme-linked immunosorbent assay (ELISA). Samples were collected over a period of 10 months (December 2014 -September 2015. Results obtained were analyzed using Statistical Package for Social Sciences (SPSS) version 20.0 statistical software; Chi-square (χ 2 ) test was utilized to assess the association between the sociodemographic variables and HEV status while Logistic regression was done to determine the strength of association between the potential risk factors and HEV status (statistical significance was set at P ˂ 0.05). The overall anti-HEV prevalence was 2.7% (5/186). The highest seroprevalence was in the age range 15-25 (4.1%) years. Males had higher prevalence (3.2%). None of the sociodemographic status and potential risk factors were significantly associated with HEV infection (P ˃ 0.05). Preventive public health measures should be maintained among individuals and communities. Data suggest further research with larger population as HEV remains an under-recognized public health challenge.
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