The present study aimed to the determined incidence of Dermatophillosis among one humped camel (Camelus dromedarius) provided to Tamboul livestock market, Sudan. Three hundred camels of different ages and sex that came from different parts of Sudan were studied in different season's assessment of some factors on the incidence of Dermatophillosis, and haematological and biochemical values for infected camels were done. The results showed that the incidence rate of Dermatophilus infection in camels was 3%, visually; loss of hair and accumulation of necrotic white materials around the neck, forelimb, thorax and sometimes all parts of the body was shown; the necrotic white materials were deep and hard attachment with skin. M icroscopically the Dermatophilus congolensis under the microscope revealed cocci was used 10% KOH and Giemsa stain. According to age, Chi-square revealed a significantly higher incidence rate in the age group less than 6 years (88.9%) followed by 6-12 years (11.1%) years and not noted in ages more than 13 years. Therefore, a high significance variation in sex and all infected camels were noticed in male. While the season factor showed an insignificant effect on Dermatophilus infection. In addition, the results showed that Dermatophilosis was an insignificant effect on the mean of hematological and biochemical parameters (p>0.05). Dermatophillosis mixed with dermatophytosis was detected in most examined samples. Direct examination using 10% KOH is a reliable technique to determine chronic Dermatophillosis and the Strategic application of anti-biotic drugs mixed with anti-fungal drugs for the treatment of camel Dermatophillosis is strongly recommended.