Twenty-nine cases of primary megaureter diagnosed before the age of 3 months are grouped in this diagnostic and therapeutic study. Seventy-five per cent were discovered by antenatal sonography due to the presence of pelvicalyceal dilatation without localising precisely the position of obstruction, twenty-five per cent were detected by the occurrence of early urinary tract infection. Four patients were operated during the first few months. 2 diversions and 2 reimplantations. Fifteen including the 2 with early diversion were submitted to later reimplantation at the average age of 15 months. 12 patients were treated conservatively by antibiotics and regular supervision. The respective results of the operated and non-operated patients were evaluated comparing the initial dilatation and the last IVU using the classification of Beurton. Regardless of the marked initial dilatation, significant spontaneous regression or complete resolution were often seen during the first year of follow-up. Thus surgery should be deferred initially even for the severely dilated forms, except in a few critical cases where a diversion is indicated. Reimplantation should be deferred for some months unless deterioration is noted, or performed only after one year or 18 months if regression is insufficient, thus optimising operative conditions.

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Background: Operative hysteroscopy with lysis of intrauterine adhesions is a viable treatment option for Asherman syndrome. However, with all forms of adhesion resection, there is a high rate of reformation of intrauterine adhesions. The current study will focus on a unique technique to evaluate the use of platelet rich plasma over an inflated balloon versus conventional method (inflated balloon). Aim: This study aim to assess the efficacy of the platelet rich plasma in preventing reformation of intrauterine adhesions after adhesiolysis in cases of Asherman syndrome. Materials and Methods: This study was conducted in Ain-Shams Maternity Hospital (Early Cancer Detection and Endoscopy Unit) during the period between July 2019 and February 2020. Forty patients seeking for conception with a history of primary or secondary infertility with severe intrauterine adhesions; 20 patients (case) injected with PRP and 20 patients (control) with IU balloon. Results: Our study showed a significant increase of menses duration among the PRP group post-operative (3.0±1.1) days and preoperative menses duration (1.5±1.4) days compared to balloon post-operative (1.9±1.6) and preoperative (1.5±1.6) days. The study also showed significant increase of menses amount among the PRP group post-operative (5.2±3.7) pads, and preoperative menses duration (1.0±1.0) pads compared to balloon post-operative (2.9±3.2) and preoperative (0.9±0.9) pads. Conclusion:Platelet rich plasma after operative hysteroscopy has high efficacy and safety in improvement of menses duration, amount and adhesion score in cases suffering from severe intrauterine adhesions and decreasing postoperative adhesions.