Background: Escherichia coli rng gene (previously called cafA) encodes a novel RNase, named RNase G, which is involved in the 5 0 end-processing of 16S rRNA. In rng mutant cells, a precursor form of 16S rRNA, 16.3S rRNA, is accumulated. Here we report a role of RNase G in the in vivo mRNA metabolism.
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