The aim of this study is to analyze the meditative role of emphatic tendency in the relationships among social exclusion, loneliness and subjective well-being in school in adolescents. The sample of the study is composed of 601 volunteers (301 female and 290 male) of high-school students. Data are collected by the application of the following scales: Brief adolescents' subjective well-being in school scale (BASWBSS), ostracism experience scale for adolescents, social and emotional loneliness scale and KA-Sİ emphatic tendency scale. Two-step structural equation modelling is employed in this study to determine the role of social exclusion and loneliness on school well-being of adolescents through the meditative role of emphatic tendency. As a result of SEM, regarding the direct influences, it is found that both social exclusion and loneliness predict emphatic tendency in a negative direction. On the other hand, it is understood that the emphatic tendency predicts school well-being in a positive direction. When indirect influences are examined, it is understood that social exclusion effects school subjective well-being via the mediation of empathic tendency negatively with a standardized effect coefficient of -.34 while loneliness effects school subjective well-being via the mediation of empathic tendency negatively with a standardized effect coefficient of -.14. When the fit indices for the model are considered, all the indices can be said to be at acceptable levels. Findings are discussed in the context of related literature.© 2017 IOJES. All rights reserved Keywords: 1 Adolescence, social exclusion, loneliness, school subjective well-being, empathic tendency. Extended Summary PurposeThis study tries to determine the meditative role of the emphatic tendency on the adolescents' school well-being in its relationship with social exclusion and loneliness. Many scholars (Hunter, 2003;Haigh, 2009) agree that empathy has an important role in understanding and explaining social behaviour. MethodThe sample consists of 601 volunteering students of which 311 are female (51.7 %) and 290 are male (48.3 %). The students are chosen by stratified sampling from among different types of high schools and are in different grades. The sample is determined with regard to the number of students attending sub-types of high-school population and their percentage (25 %). Participants constituting the sample are aged between 14 and 18. The mean age of the participants is 16.07 with a standard deviation of 0.94.