Purpose: To assess the 3-year survival rates and the incidences of biological and technical complications of all-ceramic and metal-ceramic tooth-supported single crowns. Material and methods: An online research of literature on Pubmed was conducted independently by 3 reviewers to identify the clinical studies performed from 2000 up to 2017 and completed by a manual research. Keywords, inclusion and exclusion criteria were well-defined. Results: The research revealed 501 titles and led to a final analysis of 31 full text articles. Only 6 studies met the inclusion criteria and reported on 215 metal-ceramic and 501 all-ceramic TSSCs. The meta-analysis of the included studies indicated an estimated survival rate of metal-ceramic TSSCs of 90.14% (95% CI: 89.72%-91.35%) after 3 years. This was a little bit higher than the estimated 3-year survival rate of Lithium-disilicate (89.54%; 95% CI: 87.18%-91.89%). However the 3-year survival rate, of Zirconia TSSCs was statistically much higher (92.01%; 95% CI: 89.58-94.43%). When the outcomes in anterior and posterior regions were compared, Zirconia and Lithium-disilicate TSSCs exhibited survival rates of 91.64% and 91.12% respectively, in the posterior region, where metal-ceramic TSSCs exhibited only 90.14% as a 3-year survival rate. As for the anterior region, we could only compare the TSSCs made out of Lithium-disilicate and Zirconia as the metal-ceramic ones were all laid on the posterior regions. Zirconia performed the highest 3-year survival rate in the anterior region (93.54%; 95% CI: 91.08-96%) whereas Lithium-disilicate showed only 87.5%. This was due to the low level of the mechanical properties of such material, which clinically indicated by major chipping and tooth fracture. Conclusion: Survival rates of metal-ceramic crowns were nearly similar to those reported for most types of all-ceramic TSSCs in the posterior region. Weaker Lithium-disilicate-based ceramics should be limited to application in the anterior region, even if they expressed a higher survival rate in the anterior regions. Zirconia-based TSSCs should not be considered as a primary option due to their high incidence of technical problems. Keywords: Tooth-supported single crowns; Fixed dental prosthesis; All-ceramic; Metal-ceramic; Survival; Technical complications; Biological complications;