BackgroundMalnutrition is common in patients diagnosed with chronic obstructive pulmonary disease (COPD). CRP/albumin ratio (CAR) can be used as a parameter to evaluate the inflammatory process and nutritional status together. The aim of this study was to make a general evaluation of the nutritional status of hospitalized patients with COPD and to investigate whether CAR can predict nutritional status in these patients. MethodsPatients who were hospitalized with COPD who were consulted to the nutrition department were included in the study. The patients' Nutritional Risk Score-2002 (NRS), demographic data, diagnoses, body mass indexes (BMI), nutritional support applied to the patients were recorded. CRP, Albumin, and CAR values of the patients were determined. Patients recommended nutritional follow-up, total parenteral nutrition (TPN) or enteral nutrition (EN) initiated, and oral nutritional supplement (ONS) support were identified. ResultsA total of 393 patients with COPD were analyzed. 88.55% of the patients were in the NRS ≥ 3 risk group. TPN treatment was started in 10.2% of the patients, EN in 10.9%, ONS in 76.3%, and nutritional follow-up was recommended in 2.5% of the patients. While albumin level was lower in patients with NRS ≥ 3, CRP and CAR were higher in patients with NRS ≥ 3 (p < 0.05). There was a negative correlation between NRS-2002 and albumin (p < 0.001). A positive correlation was observed between NRS-2002 and CRP and CAR (p < 0.001). Age and CAR were found to be effective in predicting those with NRS-2002 ≥ 3. The cut-off value for CAR was accepted as 3.26. ConclusionsThe need for nutritional support is high in patients hospitalized with COPD. It is important to evaluate nutritional support needs in these patients, regardless of NRS-2002 and BMI. In this respect, the clinician's observation and the decision are as valuable as the scoring that determines malnutrition. We think that the cut-off value of 3.26 determined for CAR can be used in the nutritional risk assessment in patients with COPD.
The current study determined that FVC% is important in the prediction of mortality. Moreover, it demonstrated a strong relationship between exercise desaturation and PH.
ÖZETAmaç: Kardiyopulmoner hastalığı olanlarda sigara bırakma oranlarını belirlemek ve kardiyopulmoner hastalık dışında eşlik eden hastalığı olanlardaki sigara bırakma oranları ile kıyaslamak.Yöntemler: Eylül 2004 ve Ocak 2008 tarihleri arasında aktif sigara içen ve eşlik eden hastalığı olan 202 hasta prospektif gözlemsel bu çalışmaya alındı. Hastalar Fagerstrom nikotin bağımlılık testini ve genel özellikleri değerlendirmeyi sağlayan anketi cevapladılar. Başlangıç solunum fonksiyon testleri ve karbonmonoksit ölçümleri yapılan tüm hastalara davranış tedavisi verildi. Farmakolojik tedavi olarak nikotin replasman tedavisi, bupropion veya kombinasyon tedavileri başlandı. Olgular sağlıkla ilişkili kayıtlarına göre, kardiyopulmoner hastalığı olanlar (124) ve kardiyopulmoner hastalık dışında eşlik eden hastalığı olanlar (78) olmak üzere iki gruba ayrıldı. İstatistiksel değerlendirmede Student t ve Ki-Kare testleri kullanıldı. Bulgular: İki grubun sigaraya başlama yaşları benzerdi ancak, kardiyopulmoner hastalığı olan grubun toplam tütün tüketimi daha yüksekti (p<0.05). Aynı grubun %51'i var olan hastalıkları nedeniyle sigarayı bırakmak istiyordu (p<0.05). Bunların dışında iki grup arasında tedavi protokolleri de dahil olmak üzere farklılık yoktu. Kardiyopulmoner hastalık grubunda sigara bırakma oranları (%40) diğer gruba göre daha düşükken, tekrar sigaraya başlama oranları da daha yüksekti (%12) (sırası ile p<0.01 ve p=0.01). Alt grup analizlerine bakıldığında ise kardiyopulmoner hastalığı olanlarda hiçbir tedavinin diğerine üstün olmadığı görüldü (p>0.05). Sonuç: Bu çalışmanın sonuçları, kardiyopulmoner hastalarda tütün bağımlılığının önemli ve üstesinden gelinmesi zor bir sorun olduğunu göstermek-tedir. Diğer taraftan bu hastalarda seçilecek tedavi tipinin sigara bırakma başarısını etkilemediği görülmektedir. (Anadolu Kardiyol Derg 2011; 11: 244-9) Anahtar kelimeler: Kardiyopulmoner hastalık, sigara bırakma, tütün ABSTRACT Objective: To determine the smoking cessation rates of outpatients with cardiopulmonary disease and the differences between non-cardiopulmonary diseases. Methods: Two hundred and two active smokers with comorbid diseases were prospectively evaluated between September 2004 and January 2008 in this observational study. All of the patients answered Fagerstrom test for nicotine dependence with a regular questionnaire of general characteristics. Behavioral counseling therapies were administered to all of the subjects. Nicotine replacement therapy, bupropion or combination therapies were the pharmacological therapies after running the baseline spirometry and carbon monoxide oximetry tests. Subjects were classified as patients with cardiopulmonary disease (124) and non-cardiopulmonary diseases (78), based on medical history. Student t and Chisquare tests were used for statistical analyses. Results: The age of smoking was similar but total amount of smoked tobacco was higher (p<0.05) in the cardiopulmonary diseases group. In this group, the main smoking cessation reason was the existing disease (51%) (p<0.0...
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