The need to communicate, as an important human need, can be secured through attending public spaces such as the cultural environment, especially in developing countries where women do not prefer visiting these spaces alone. By using 304 questionnaires, the present study investigated the influence of cultural centres’ factors in social interactions of women over 18 years old in Tabriz, Iran. Confirmatory factor analysis identified that behavioural, environmental, perceptional, structural and social aspects have significant influence on women’s social interactions. In addition, Friedman test indicated that behavioural aspect has the most and social aspect has the least influence. The findings of the present study can be utilized by architects and urban authorities.