Melatonin premedication was associated with preoperative anxiolysis and sedation without postoperative impairment of psychomotor performance.

Background. Different methods and propofol formulations have been used to decrease propofol injection pain, but it remains an unresolved problem. We aimed to investigate the effect of i.v. acetaminophen pretreatment on the propofol injection pain.

BACKGROUND In search of an optimal drug for I-gel insertion, in our study, we have compared two group of drugs dexmedetomidine with propofol and fentanyl with propofol.