COVID-19 is a disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The introduction of vaccines against COVID-19 caused great enthusiasm around the world as immunization might end the pandemic. However, it was previously stated that COVID-19 cases would rarely continue to occur despite immunization. Fourteen days after the second dose of the vaccine, a 66-year-old male patient with a negative COVID-19 PCR test result and high levels of IgG and low levels of IgM-A against SARS-CoV-2 was admitted to our intensive care unit (ICU) due to the clinical picture of Acute Respiratory Distress Syndrome (ARDS). We aimed to stress the need for continuing preventive measures in vaccinated individuals, too, by presenting the clinical findings of the patient, who was considered to have developed ARDS due to COVID-19, as high levels of IgG and IgM-A against SARS-CoV-2 were detected on day 8 during ICU admission.

Rectus sheath hematoma is defined as the accumulation of blood within the rectus sheath caused by tears in the epigastric arteries or the rectus muscle fibres. Although seen rarely, the use of anti-coagulants has been held responsible as the most common predisposing factor in the etiology of autoimmuune diseases. Systemic lupus erythematosus (SLE) is a disease which is challenging in diagnosis and management both in respect of multiple clinical responses to the disease and various complications. Hemorrhagic markers have a place in the clinical manifestation of the disease. The case is here presented of a 78-year old male patient who was admitted to the Intensive Care Unit (ICU) with a diagnosis of pneumonia, and during hospitalisation was diagnosed with SLE and rectus sheath hematoma. The points which can be discussed in this case are that there was no history of anticoagulant use, and despite the coagulation function test results in the normal range and the order of low-dose (40 mg/day) enoxiparin sodium as thromboembolism prophylaxis in the first 2 days of admittance, this is the first reported case of spontaneous giant rectus sheath hematoma where SLE was held responsible as an etiological factor.

Aim: Changes in the iron level in the myocardium may be affected by sodium and potassium channels in myocytes and there may be a contribution to the etiology of cardiac arrhythmia. The aim of this study was to examine for the first time in literature how the Tp-e interval, which has been accepted in recent years as a strong ventricular repolarisation index, is affected in female patients with severe iron deficiency anemia. Material and Methods:The study included a total of 64 participants, as a study group of 34 patients diagnosed with severe iron deficiency anemia (Hgb<8g/dL Ferritin<14 mcg/L, MCV<80 mm 3 ) and a control group of 34 subjects. To determine the QTc and Tp-Te interval durations, manual examination was made of manual precordial V5 lead ECGs taken routinely on the presentation of all participants. Results:The Tp-e interval was determined to be statistically significantly shorter in the patients (78.97 ± 8.63 ms) compared to the control group (84.57 ± 10.13 ms) (p<0.05). A positive relationship was determined between Tp-e and QTc durations and Hgb and ferritin levels (p<0.05). Conclusion:The results of the study showed that the QTc duration and the Tp-e duration were shorter in female patients with iron deficiency anemia, and therefore iron deficiency anemia can be discounted as a cause of prolonged QTc and Tp-e durations.

Objective: Both mean platelet volume (MPV) and platelet distribution width (PDW) can be used for various clinical results. The aim of this study was to establish a clinicopathological relationship by examining the thrombocyte parameters of subclinical hypothyroidism (SCH) cases.Methods: A retrospective evaluation was made of 60 female subjects as a patient (subclinical) group of 30 females and an age-matched control group of 30 females. Results:The mean age was similar in both study groups as 34.9 ± 4.9 years in the patient group and 33.8 ± 3.19 years in the control group (p>0.05). The MPV and PDW values were measured higher in the patient than control group (p< 0.05).TSH and platelet parameters, there was determined to be a correlation between MPV (r=0.259, p<0.05) and PDW (r=0.269, p<0.05). Conclusion:As a result, elevated MPV and PDW levels in patients with SCH may predispose for cardiovascular diseases.

Çalışmamızda yoğun bakım ünitesinde tedavi edilen zehirlenme olguları retrospektif incelenerek ilimize ait zehirlenme vakalarının profilini belirlemek, epidemiyolojik çalışmaların güncellenmesine ve ülkemizin zehirlenme verilerine katkıda bulunmak amaçlandı.