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To our best knowledge, our study is the first study in the literature. Although the role of specific mechanisms in SHL is not entirely understood, the capillaroscopic examination can show the importance of microvascular function in SHL. CD and PORH values were found to be low in SHL patients, and a low PORH value was found to be a factor of poor prognosis.

Percutaneous penetration of chemicals from clothing can result in both acute and chronic toxicities. Although personal protective equipment composed of nonwoven material can provide thorough protection, it is often uncomfortable under normal occupational conditions. Certain everyday textiles are often utilized as protective clothing due to their cost, comfort, and convenience. Although common textiles may cover most skin, certain regions remain exposed by such outfits. The body areas covered by the fabric are at risk for fabric permeation and percutaneous penetration of chemical, either immediately or over time, dependent on the fabric composition and the characteristics of the chemical used. in vitro and in vivo publications studied percutaneous penetration of chemicals from contaminated fabric and show that everyday textiles are superior to bare skin. The increased protection offered can be attributed to properties of the fabric such as weave, thickness, fabric finish, absorbency, and the overall barrier provided. Although common textiles do offer some protection, they remain inferior to nonwoven personal protective equipment. Much remains unknown regarding percutaneous penetration and protection offered by everyday textiles.

The aim of this study was to evaluate whether pediatric obstructive sleep apnea syndrome (OSAS) secondary to adenoid hypertrophy causes systemic microvascular dysfunction. This is a prospective single-blinded case-control study. As the patient group, 81 patients diagnosed to have OSAS secondary to adenoid hypertrophy at our hospital between January 2016 and May 2016; as the control group, 26 healthy pediatric volunteers who presented to the hospital for health screening were included in this study. Three groups of OSAS patients were defined as mild, moderate, and severe respectively, according to the lateral nasopharynx x-ray. Patients with comorbid diseases were excluded from the study. For microvascular dysfunction, videocapillaroscopic evaluation was performed at the nailfold and capillary density (CD) and postocclusive reactive hyperemia (PORH) values were measured and statistical analysis between the groups was performed. The duration of complaints in all patients with OSAS was at least 6 months and <1 year. CD measurement in the control group and mild, moderate, and severe OSAS group was 94.1 ± 7.9, 96.9 ± 11, 94.7 ± 8.4, and 93.7 ± 9.4, respectively, with no significant difference between the groups (P > 0.05). PORH measurement in the control group and mild, moderate, and severe OSAS group was 95.6 ± 8.6, 97.9 ± 10.1, 96 ± 8.7, and 93.9 ± 9.3, respectively, with no significant difference between the groups (P > 0.05). OSAS secondary to adenoid hypertrophy in pediatric patients was demonstrated to cause no dysfunction in microvascular circulation and carried no cardiovascular risk in the early period.

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