Introduction: Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis and usually attacks the lungs. Indonesia is in the third rank of TB cases in the world. An important concern regarding TB currently is the case of anti-TB drug resistance, hence research on resistance patterns and risk factors is essential. This study aimed to identify the pattern of first-line anti-TB drug resistance at Dr. Soetomo General Hospital, Surabaya.Methods: A descriptive retrospective study was conducted at Dr. Soetomo General Hospital, Surabaya for the period of 2017-2019. The samples were obtained through total population sampling of 239 pulmonary TB patients with first-line anti-TB drug resistance which were registered at MDR-TB Polyclinic Dr. Soetomo General Hospital, Surabaya. Only complete medical records were included. The variables were first-line anti-TB drug resistance (isoniazid, rifampicin, ethambutol, streptomycin) and patients’ characteristics (age, gender, treatment history, and comorbidities). The drug resistance test was performed using certified culture methods.Results: Among 239 patients, the incidences of resistance to H, R, E, and S were 79.08%, 94.14%, 25.94%, and 20.08%, respectively. The most common patterns were HR (42.26%), R (18.83%), and HRE (12.55%). The largest age group was 45-54 years old (38%). The dominant gender was male (56.49%). The most treatment history category was relapsed patients (48%) and there were more patients with comorbidity (57%).Conclusion: The highest incidence rate of resistance was rifampicin and the most common resistance pattern was HR. Most of the patients were of working age, male, relapse patients, and had comorbidities. An appropriate TB therapy treatment plays an important role in preventing resistance.

Introduction: Taro village has a higher risk of gathering the people since it is one of the most popular tourism sectors in Bali hence increasing the potential to spread coronavirus disease 2019 (COVID-19). The level of knowledge plays an important role in determining whether the society is ready to implement the health protocols or not. This community service aims to evaluate the level of knowledge regarding COVID-19 health protocols in the tourism sector in the Taro village. Method: This research was conducted using a quasi-experimental one-group pretest-posttest design in Taro village, Bali. Respondents filled out the questionnaire before and after counseling. The questionnaire consisted of 10 items of knowledge. The participants were Taro’s residents who met inclusion and exclusion criteria. A total of 31 respondents were taken. The data were tested for normality with the Kolmogorov-Smirnov test and analyzed with paired T-test using the IBM SPSS statistics version 25. Significance was determined at a 5% level (P-value ≤0.05). Results: A total of 31 valid filled-questionnaires were collected. In general, Taro’s residents’ knowledge regarding COVID-19 health protocol in the tourism sector was sufficient, but some topics are still insufficient. The mean score before counseling was 79,03 ± 1,340 while the mean score after counseling was 86,13 ± 1,366. There was a significant difference (p<0,05) on level of knowledge (p=0,000) before and after counseling. Conclusion: There was a significant difference in the level of knowledge of Taro village’s residents toward COVID-19 health protocols in the tourism sector before and after counseling.

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