The making of perfume from the combination Magnolia alba (M. alba) flower oil, Cananga odorata (C. odorata) and Mimusops elengi L (M. elengi) fixed with Pogostemon cablin oil (P. cablin) have been done. Essential oil of M. alba and C. odorata was distilled by water distillation and extraction essential oil of M. elengi flower using n-hexane evaporated solvent method. Composition perfume through organoleptic test obtained with a ratio of 4% v/v, 4% v/v, and 2% v/v for each essential oil M. alba, C. odorata and M. elengi. Antibacterial activity of the perfume and each of the volatile oil was performed by the disc diffusion method. Antibacterial activity test showed that perfumes were able to inhibit the growth of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) bacteria, but less active. Antibacterial activity of the perfume was more active against E. coli with an inhibitory zone of 8.3 mm and 39.81% inhibitory power than S. aureus bacterial 7.3 mm inhibition zone with 37.55% inhibitory power. Perfumes after storage for one, and two months had better antibacterial activity than before storage with an average inhibitory zone of 11-15 mm and inhibitory power of 50- 68,18%. Keywords: Antibacterial, E. Coli, C. Odorata, M. alba, M. elengi, P. cablin, , S. aureus
Acne vulgaris or acne is a chronic inflammatory skin disease in adolescents and adults affecting one self-confidence. The result of the research shows the ethanol extract, subfraction, pure isolate, and gel extract of Artocarpus camansi are active in inhibiting the growth of Propionibacterium acnes. The ethanol extract with the highest inhibition zone was at the concentration of 0.5 and 2% with 9.1±0.62 mm and 8.5±0.7 mm with the activity of 47.07% and 43% respectively (in comparison with the chloramphenicol 30 μg 19.33±0.47mm). The gel extract had the highest activity at 2%, with an inhibition zone of 8±0.50 mm and the activity of 43.97%. Anti-acne activity for all subfractions had an activity of 32.5-33.3% while the pure isolate was at 42.10 - 45.63%. Physical properties of the gel extract were evaluated for four weeks by examining the pH test obtained with a range of 5.8-6.7, viscosity in the range of 18460-19668 cP, spreadability in the range of 5.45-7.20 cm, adhesion observation above 4 seconds, and homogeneity in a concentration of 0.5-7.5%. The pure isolate has a melting point of 147 ℃, presumed to be γ-sitosterol and appropriate with the screening phytochemicals results with the presence of steroid.
The enrichment of beta-carotene concentration from crude palm oil (CPO) using nanofiltration polyethersulfone (NF-PES) membrane was studied. This work begins with preparing the NF-PES membrane via the phase inversion method as the first stage. PES polymer was used as base membrane material and N-Methyl-2-Pyrrolidone (NMP) as a solvent. Then, the process concentration of beta-carotene was conducted by filtration of the red palm methyl ester as feed solution using dead-end mode filtration. The objective of this work was to evaluate the effect of separation pressure (3; 4; and 5 bar) on beta-carotene concentration from the feed solution. SEM results showed that the NF PES membrane had an asymmetric structure. It consisted of two layers: the thin top layer had a dense structure, while the support layer had a sponge-like structure. Besides, the pure water permeability of NF PES membrane was about 2-18 L/m2.h.bar was fitted within the range of NF membranes. The optimum operating pressure that gives the highest beta-carotene concentration was achieved at 3 bar. As a result, the beta-carotene concentration has improved about 1.14 times compared to the initial beta-carotene concentration in the feed solution.
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