Background:Dyspepsia is a common disorder that can present many clinical dilemmas in patient management. Although not usually life-threatening, its symptoms such as abdominal pain, heartburn, early satiety and postprandial fullness can have a significant negative impact on patients' quality of life.Objectives:The aim of this study was to determine the prevalence of dyspepsia and its associated factors among the adult population in Kerman in 2010.Patients and Methods:This cross-sectional study was performed on 2210 patients with the mean age of 43.4 years in Kerman, a city in southeast of Iran. Demographic factors, lifestyle data and gastrointestinal symptoms were collected for each patient.Results:The prevalence of dyspepsia was 16.1% (95% confidence interval: 14.3-18.1). The prevalence in patients with abdominal obesity (7.3%) was lower in comparison with those with low physical activity (13.8%). Out of other psycho-behavioral risk factors, anxiety after controlling for other variables increased the risk of functional dyspepsia more than 65 percent (P = 0. 004) and depressive disorders also increased that risk about 2.13 percent (P < 0.0001). Patients with dyspepsia symptoms were more likely to restrict their diet, take herbal medicine, use over-the-counter drugs and consult with physicians.Conclusions:Results of this study reveal the moderate prevalence of dyspepsia among the adult population in Kerman like in other parts of the country and this prevalence is associated with several demographic factors, lifestyle and health-seeking behaviors.

Background Neonatal phototherapy (NNPT) has long been used as an effective and relatively safe method of treating neonatal hyperbilirubinemia. Considering the subsequent evidence of long-term impacts of NNPT such as malignancies, this study was conducted to evaluate the relationship between NNPT and childhood cancers. Methods This case-control study assessed 116 children up to 4 years old with every kind of cancer referred to the Oncology department of Afzalipour hospital, Kerman, Iran, from 2011 to 18. Moreover, 116 pediatric patients without cancer hospitalized at the same Center were included after sex and age matching as the control group. The history of phototherapy and its duration were evaluated in these two groups. Results We found no association between the NNPT and malignancies in children. However, high intensive phototherapy was higher historically among affected cancerous patients than in non-cancerous cases without any statistically significant difference (25% vs 19%; P = 0.26). Maternal educational level and history of maternal infection during pregnancy, which initially appeared to be two factors associated with malignancy in single variable regression analyses, were not significant based on the adjusted models. Conclusions The results did not show a positive correlation between NNPT and childhood cancers, which may partly be due to the relatively small sample size of the study. However, some other evidence is worrisome enough that NNPT should not be considered risk-free. Additional multi-centric studies should be undertaken to specify that phototherapy is really safe.

Background: Gastrointestinal (GI), liver, and pancreaticobiliary diseases, in addition to the high health care utilization, account for a significant proportion of disability and death in Iran. We aimed to assess the incidence of in-hospital mortality for the total GI, liver, and pancreaticobiliary diseases in all hospitals in Kerman, Iran. Methods: In a cross-sectional study from May 2017 to April 2018, we collected the data of in-hospital death records due to GI, liver, and pancreaticobiliary diseases in all hospitals in Kerman city. GI and liver diseases were classified into three main categories: 1. Non-malignant GI diseases, 2. Non-malignant liver and pancreaticobiliary diseases, and 3. GI, liver, and pancreaticobiliary malignancies. All data were analyzed using SPSS software, version 22 (IBM). Results: Of 3427 in-hospital mortality, 269 (7.84%) deaths were due to GI, liver, and pancreaticobiliary diseases, of which 82 (30.48%) were related to non-malignant GI disorders, 92 (34.20%) to the non-malignant liver and pancreaticobiliary diseases, and 95 (35.31%) were associated with GI, liver and pancreaticobiliary malignancies. Most patients were male (62.08%), and the most common age was between 60-80 years (40.5%). GI bleeding occurred in 158 (58.73%) patients, and variceal bleeding was the most common cause (28.48%). Additionally, cirrhosis was reported in 41 out of 92 (44.56%), and hepatitis B virus (HBV) was the most common cause of cirrhosis among 17 out of 41 (41.46%). Conclusion: Our results show that gastric, colorectal, and pancreatic cancers and cirrhosis due to HBV were the most common causes of mortality associated with GI, liver, and pancreaticobiliary diseases in the hospitals of Kerman.

No abstract