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Background: This study was designed to determine the accuracy of bronchoalveolar lavage fluid cytology (BAL) using histopathologic examination of transbronchial biopsy specimens as the gold standard in diagnosis of lung carcinoma at our center. Materials and Methods: A retrospective study was conducted to investigate a total of 388 patients who were suspected of having lung cancer and had undergone fiberoptic bronchoscopy in Shahid Sadoughi hospital from 2006 to 2011. Lung masses were proven to be malignant by histology. Results: Transbronchial lung biopsy (TBLB) identified malignancy in 183 of the 388 cases, including 48 cases (26.2%) with adenocarcinoma, 4(2.1%) with bronchioloalveolar carcinoma, 47(25.6%)with squamous cell carcinoma, 34(18.5%) with well-diffentiated neuroendocrine carcinoma, 35(19.1%) with small cell carcinoma, 14 (7.6%) with non-small cell carcinoma, and 1 (0.54%) with large cell carcinoma. A total of 205 cases were correctly classified as negative. BAL was also performed in 388 patients; 86/103 cases were consistent with the final diagnosis of lung cancer and 188/285 cases were correctly classified as negative. The sensitivity of BAL was 46.9%(CI:41.9%, 51.8%)) and its specificity was 91.6%(CI:88.8%, 94.3%). BAL had a positive predictive value (PPV) of 83.4%(CI:79.7%, 87.1%) and a negative predictive value (NPV) of 65.8%(CI:61%, 70.5%). The overall accuracy of BAL was 70.5% and the exact concordance was 39%. Conclusions: Our findings suggest that BAL cytology is not sensitive but is a specific test for diagnosis of lung carcinoma. If transbronchial lung biopsy is combined with bronchoalveolar lavage, the positive diagnostic rate will be further elevated.

Objective: Recently, social media use has become prevalent in the daily lives of many adolescents. This study was performed to address adolescents’ sleep quality and depression in relation to social media use. Method: This cross-sectional cluster-sampling study was directed on 576 high school students in 2019 in Hamadan, Iran. Three standard self-reported questionnaires were used for recording sleep patterns (Pittsburgh Sleep Questionnaire Index (PSQI)), depression (Beck), and Electronic Media Use. Data was analyzed using SPSS. P-values less than 0.05 were considered as being significant. Results: Among the adolescents 290 (50.3%) were female and the age median was 17. The average time of all Smart devices used was 7.5±4.4 hours per day. Among all students 62.3 % (359) said that they had their cell phone on in their bedroom when they sleep. In boys, the amount of social media use was significantly more than girls and poor sleep quality had a statically significant relationship with social media use (P-Value = 0.02). Additionally, there was a reverse correlation between the average use of electronic devices and sleep duration (Spearman’s rho = 0.17; P-Value = 0.03), and a direct correlation between the average use in social media and depression (Spearman’s rho = 0.171; P-Value < 0.001). Conclusion: In this important age group a high level of electronic devices use and its relationship with sleep quality, daily dysfunction, sleep duration and depression is worthy of issue awareness among health managers, parents and teachers for providing interventional programs, based on standard updated guidelines, in order to reduce the problem and familiarize adolescents and their parents, at home or school, with restrictions on using devices to view and participate in social media

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Background:Child abuse is an issue that has many physical and psychological consequences.Objectives:This study was designed and conducted to investigate the current situation regarding child abuse, which can be used as a guideline for planning future interventions.Materials and Methods:This was a descriptive, analytic cross-sectional study on 700 Yazd secondary school students in 2013, using a standardized self-administered questionnaire. The collected data was analyzed using the SPSS v.19 software and appropriate statistical tests and logistic regression analysis. P values of < 0.05 were considered statistically significant.Results:Overall, 700 students (43%) were boys. Child abuse frequency was 93.5% (92.2% of boys and 94.4% of girls). The most common domains of child abuse among all students were neglect (83.8%), psychological (76.1%), physical (36.1%) and sexual (28.8 %), respectively. The most common domains of child abuse among female students were neglect (84.9%), psychological (82.3%), physical (32.5%) and sexual (31.5 %), and among male students, these were neglect (82.3%), psychological (67.9%), physical (41%) and sexual (25.3%). Demographic variables included substance abuse of parents, father’s education, parents living status and having other jobs, which were significantly related variables to child abuse and neglect (P value < 0.05).Conclusions:Our study is the first investigation performed on patients with LCH and its possible association with EBV in Iran. Considering the P = 0.004, which is statistically significant, the findings do support the hypothesis of a possible role for EBV in the pathogenesis of LCH. These results are in accordance with several previous investigations, with positive findings.