Background Human immunodeficiency virus and acquired immunodeficiency syndrome had created enormous challenges worldwide, and continues to be the world’s serious health and development challenges. Globally, at the end 2017, there were 1.8 million children (< 15 years) living with HIV. The survival of HIV-positive children treated with ART depends on a variety of factors, which might vary greatly with economic, socio-demographic, behavioral risk, and health factors. This study aimed to assess survival status and predictors of mortality among HIV-positive children on antiretroviral therapy at East Gojjam Zone Public hospitals, Northwest Ethiopia. Methods An institution-based retrospective cohort study was conducted in selected hospitals of the East Gojjam zone, Northwest Ethiopia, among < 15-year-old children who were newly enrolled in HIV care clinic from January 1st, 2014 to December 31, 2018. Data were collected from patient charts from March 1 to 22, 2019 using a standardized checklist. Data were analyzed by SPSS version 24. A Kaplan–Meier curve and log-rank test were used to estimate the survival time and compare survival curves between variables. Multivariable Cox proportional-hazards model was fitted to identify predictors of survival status taking p-value < 0.05 as statistically significant. Result In this study, a total of 251 HIV-positive children on ART were followed up for a total of 60 months, with a mean survival time of 55.54 (± 0.83) (95% CI: 53.90–57.17) months. The overall mortality incidence rate in the cohort during the 626 Child-Year-Observation (CYO) was 2.56/100 CYO. The overall estimated survival probability after starting ART was 0.90 at 60 months of follow-up. In this study age < 5 years, Hgb < 10 gm/dl, CD4 count below threshold, cotrimoxazole preventive therapy, and subnormal weight for height were statistically significant predictors of survival status (P < 0.05). Conclusion and recommendation Age, hemoglobin level, CD4 count, weight for height, and not taking cotrimoxazole preventive therapy were independent predictors of mortality. Therefore, concerned stakeholders should focus on the above-mentioned predictors of mortality and nutritional interventions to enhance the survival of HIV-infected children on antiretroviral therapy.

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Background Neonatal danger signs are now a public health problem (25%) and contributing factors for neonatal death. Early detection of neonatal danger signs is an important step towards improving newborn survival. This study aimed to assess knowledge on neonatal danger signs and associated factors among post natal mothers in public hospitals of Addis Ababa Ethiopia. Methods An institutional based cross-sectional study was conducted among 363 postnatal mothers at public hospitals of Addis Ababa, Ethiopia from March 15th to May 15th, 2019. Systematic random sampling technique was used to select the study participants and semi-structure interviewer administer questionnaire was used to collect the data. The data were entered by using Epi- data version 4.4.3.1 and analyzed by using bivariable and multivariable logistic regression model with SPSS version 25.0. Then statistical significance was declared at P- value < 0.05. Finally, the data were presented by using text, figures and tables. Result All mothers expected to participate in the study were interviewed. Overall, 33.1% of mothers had good knowledge about neonatal danger signs. Factors like maternal education college and above (AOR = 2.11, 95% Cl: 1.51–2.99), caesarean section mode of delivery (AOR = 3.72, 95% Cl: 1.71–8.12), parity (AOR = 5.34, 95% Cl: 1.64–2.64), education during PNC follow up (AOR = 2.77, 95% Cl: 1.49–5.15) and identification of skilled birth attendant (AOR = 2.25,95% Cl:1.13–4.40) were significantly associated with the level of maternal knowledge. Similarly, information from health professionals (AOR = 4.54, 95%Cl: 2.16–9.70) and access to television were also statistical significant factors for maternal knowledge (AOR = 2.15, 95% Cl: 1.11–4.15). Conclusion Maternal knowledge on neonatal danger signs was poor. Therefore educational intervention during ante natal care, institution delivery and post natal care visit, advocating the use of media and increase maternal birth preparedness like identification of skilled birth attendant are highly recommended.

Background: Neonatal danger signs are now a public health problem and contributing factors for neonatal death. Early detection of neonatal danger signs is an important step towards improving newborn survival. This study aimed to assess knowledge on neonatal danger signs and associated factors among post natal mothers in public hospitals of Addis Ababa Ethiopia.Methods: An institutional based cross-sectional study was conducted among 363 postnatal mothers at public hospitals of Addis Ababa, Ethiopia from March 15th to May 15th, 2019. Systematic random sampling technique was used to select the study participants and semi-structure interviewer administer questionnaire was used to collect the data. The data were entered by using Epi- data version 4.4.3.1 and analyzed by using bivariable and multivariable logistic regression model with SPSS version 25.0. Then statistical significance was declared at P- value < 0.05. Finally, the data was presented by using text, figures and tables.Result: All mothers expected to participate in the study were interviewed. Overall, 33.1% of mothers had good knowledge about neonatal danger signs. Factors like maternal education college and above (AOR=2.11, 95% Cl: 1.51-2.99), caesarean section mode of delivery (AOR=3.72, 95% Cl: 1.71-8.12), parity (AOR=5.34, 95% Cl: 1.64-2.64) , education during PNC follow up (AOR=2.77, 95% Cl: 1.49-5.15) and identification of skilled birth attendant (AOR= 2.25,95% Cl:1.13-4.40) were significantly associated with level of maternal knowledge. Similarly, information from health professionals (AOR=4.54, 95%Cl: 2.16-9.70) and access to television were also a statistical significant factor for maternal knowledge (AOR=2.15, 95% Cl: 1.11-4.15). Conclusion: Maternal knowledge on neonatal danger signs was poor. Therefore educational intervention during ante natal care, institution delivery and post natal care visit, advocating the use of media and increase maternal birth preparedness like identification of skilled birth attendant are highly recommended.