The word 'cosmetics' is taken from a Greek word "kosmeticos" which means to adorn. Since early days materials used for beautification or improvement of appearance comes under the category of cosmetics. People want to look beautiful and the concept of cosmetics is as old as mankind and civilization. The urge to beautify one's own body and look beautiful has been an urge in the human race since the tribal days. Assorted beauty products such as skincare products, hair products, fragrances, oral hygiene, and nail products, which may contain toxic chemicals that can be harmful to health are used especially by women. Since long time cosmetics have been known to enhance the appearance of the human body. In a society obsessed with beauty, people are lured to fake their appearance as a cure for their insecurities. The estimated value of cosmetic industry today is around 20 billion dollar globally. As a consumer, we are constantly attracted in using beauty and personal care products. But these products, which are supposed to make us feel healthy and look beautiful, have a deep dark side. Various toxic ingredients and hazardous chemicals used in cosmetics are incorporated in beyond acceptable limits. These chemicals may cause serious ill effects on skin and may also enter skin and other organs causing carcinogenicity. Cosmetics have not only seeped into the fashion world but are also playing a prominent role in one's day-to-day life. Thus, it becomes a necessity to make people aware of various harmful effects of cosmetics and chemicals used in cosmetics.

Bioavailability is defined as the rate and extent (amount) of absorption of unchanged drug from its dosage form. It is one of the important parameters which are required to achieve optimal concentration of drug in systemic circulation to show a pharmacological response. A drug which has poor bioavailability shows poor aqueous solubility, slow dissolution rate, poor stability of dissolved drug at physiological pH, poor permeation through biological membrane, extensive first pass metabolism. Drugs which are poorly water soluble require high doses to obtain therapeutic plasma concentrations after oral administration of drugs. Low aqueous solubility is the major problem encountered with formulation development of new drugs. Any drug to be absorbed must be present in the form of an aqueous solution at the site of absorption. This review deals with various techniques used for the improvement of the Bioavailability of drugs. The various techniques used are size reduction, solubilising excipients, colloidal drug delivery systems, pH adjustment, solid dispersion, complexation, co-solvency, micellar solubilisation, hydrotropy etc. The article describes about various techniques which can be utilized to enhance bioavailability of drugs enhancement for their effective absorption in the body.

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Introduction: Paracetamol tablets are very common over the counter (OTC) products among the patients as a good analgesics s. It is the drug of choice in patients that cannot be treated with non-steroidal anti-inflammatory drugs (NSAID), such as people with bronchial asthma, peptic ulcer disease, hemophilia, salicylate-sensitized people and children under 12 years of age, pregnant or breastfeeding women. Objective: The objective of this study was to compare the quality of the paracetamol tablet formulations those are locally available in India pharmaceutical market manufactured by various pharmaceutical companies with pharmacopeia standards. Materials and Methods: The two popular brands (A & B) of paracetamol conventional tablet of 500 mg strength were chosen. The paracetamol tablets were obtained from the local medical shops. To compare the quality of tablet formulations of different brands various official parameters like friability, hardness, weight variation, disintegration time and dissolution were performed as per the standards mentioned in pharmacopoeia. Result and Conclusion: The result of all these parameters of different brands was in the Pharmacopoeial limits so it could be concluded that marketed pharmaceutical tablets of paracetamol of these brands are safe, effective and efficacious.