s e209 carried out. Mean age 62.8 ± 10.2 years. All patients underwent determination of creatinine, GFR by EPI, uric acid, blood lipids. CKD stages were established according to the modern KDIGO 2013 classification.Results: Among the examined patients there were 18% patients with CKDC1, GFR> 90 (n = 34); 56.3% patients with CKDC2, GFR 60-89 (n = 106); 17.5% patients with CKDC3A, GFR 45-59 (n = 33); 5.3% patients with CKDC3B, GFR 30-44 (n = 10); 2.6% patients with CKDC4, GFR 15-29 (n = 5) (p < 0.00001). 98.4% of the examined patients suffered from coronary artery disease; 46.1% had diabetes mellitus. It should be noted that patients with stage 4 CKD were significantly older (55 ± 8 vs 62 ± 9 vs 68 ± 8 vs 69 ± 9 vs 74 ± 16; p < 0.00001). According to the level of SBP, DBP, heart rate, the patients did not differ significantly.

Objective: Ambulatory blood pressure monitoring (ABPM) and home BP monitoring (HBPM) are two recommended approaches for measuring out-of-office BP. We assessed the willingness and preferences of older adults taking antihypertensive medication to complete out-of-office BP monitoring with ABPM or HBPM and if differences were present across demographic characteristics. Design and method:We conducted a survey within a prospective cohort study of patients aged 65 + years who were diagnosed with hypertension and taking antihypertensive medication within a diverse integrated health care system. Enrolled participants underwent 24-hour ABPM followed by HBPM for 7 days. Participants who completed both ABPM and HBPM were asked to fill out a self-reported survey on their willingness to undergo ABPM or HBPM if their healthcare provider suggested it, and their preferences for ABPM or HBPM. Group means were compared using t-tests. Chi-square or Fisher's exact test were used to compare group proportions. Results:We included 167 participants (mean age 74.3 years [range 65-95 years]; 55.7% female; 46.7% non-Hispanic white, 16.8% Hispanic, 15.6% non-Hispanic Black and 17.3% Asian and Pacific Islander; mean research office systolic/diastolic BP 131/68 mm Hg). Overall, 84.4% and 67.1% of participants reported that they would be completely or very willing to perform HBPM for a week and a 24hour ABPM, respectively, if their doctor thought it would be helpful to measure out-of-office BP. Also, 77.2% (n = 129) of participants preferred HBPM, 21.0% (n = 35) preferred ABPM and 1.8% (n = 3) did not have a preference. A higher proportion of females versus males preferred HBPM (Table ). There were no statistically significant differences in preference for ABPM or HBPM by age, race/ ethnicity or mean research office BP. Conclusions:The study results suggest that most older adults taking antihypertensive medication may be willing to undergo either ABPM or HBPM if recommended by their physician. However, HBPM was preferred to APBM. DC3b:0% vs 4.91% vs 13.04% vs 27.27% p < 0.001. Conclusion:AH patients with CKD have more pronounced disturbances in the daily blood pressure profile, which contribute to an increased risk of developing complications of arterial hypertension.

Purpose of the study:To study the daily profile of blood pressure in patients with arterial hypertension (AH) with chronic kidney disease (CKD).Materials and methods of the study:The study included 120 patients with AH I-III degree, who received inpatient treatment. CKD stages were determined according to the modern KDIGO 2013 classification. Daily blood pressure profile (DAP) was assessed using the Medicomcombi device (Russia).Results of the study:Among the examined patients, preserved renal function of CKDC1 (eGFR> 90 ml/min/1.73 m2) was observed in 20.8% (n = 25); CKDC2 (eGFR 60–89 ml/min/1.73m2) in 50.8% (n = 61); CKDC3A (eGFR 45–59 ml/min/1.73m2) in 19.2% (n = 23); CKDC3B (eGFR 30–44 ml/min/1.73m2) in 9.2% (n = 11) p < 0.001. CKDC4 and terminal stages were not detected. When analyzing ambulatory blood pressure monitoring (ABPM), it was revealed that according to increasing of degree of CKD, values of the average daily SBP (122.52 ± 9.25 vs 122.13 ± 12.30 vs 121.74 ± 9.43 vs 134.36 ± 15.32 mm Hg, p < 0.013) average daytime SBP (123.56 ± 8.99 vs. 124.00 ± 611.89 vs 123.74 ± 9.73 vs 134.27 ± 15.12 mmHg, p < 0.04), mean night SBP (119.80 ± 13.39 vs 116.75 ± 14.59 vs 116.09 ± 12, 04 vs 135.09 ± 16.66 mm Hg, p < 0.001) significantly rises. The load index of elevated daytime and nighttime SBP was high in AH patients with lower eGFR values. Index of SBP daytime: 13.00 ± 14.05 vs 15.43 ± 21.22 vs 10.70 ± 15.04 vs 35.10 ± 34.14% respectively, p < 0.01. Index of SAP nighttime were 33.75 ± 29.35 vs 26.04 ± 31.07 vs 26.58 ± 27.87% vs 66.10 ± 36.05% respectively,p < 0.001. A normal daily profile of SBP/DBP had 28%/32% of patients of the 1st group vs 24.61%/37.70% of patients of the 2nd group vs 37.78%/21.73% of patients of the 3rd group vs 0% /0% of patients of the 4th group, SBP p < 0.01; DBP p < 0.001. The number of non-dippers in SBP was somewhat higher in the group of patients with CKDC3b: night reduction speed (NRS) SBP 40% in group 1 vs 49.1% in group 2 vs 52.17% in group 3 vs 54.54% in group 4 group, p < 0.02. In the group of patients with CKDC3b, individuals with a daily profile of SBP/DBP “night-pickers” significantly prevailed: 32%/20% vs 14.75%/13.11% vs 13.04%/13.04% vs 45.45%/ 54.54% (in groups 1, 2, 3 and 4, respectively) in SBP p < 0.001, in DBP p < 0.001. There was a significant increase in patients with a daily profile of “over-dipper” according to DBP in patients with CKDC3b:0% vs 4.91% vs 13.04% vs 27.27% p < 0.001.Conclusion:AH patients with CKD have more pronounced disturbances in the daily blood pressure profile, which contribute to an increased risk of developing complications of arterial hypertension.