Background: Chemotherapy-induced neutropenia (CIN) is chemotherapy's most frequent myelosuppression effect. Previous studies have examined static prognostic factors to assess dynamic neutrophil changes in each cycle. This study focuses on post-chemotherapy monocytopenia as a more dynamic predictor of CIN. This research aimed to know whether post-chemotherapy monocytopenia can be used as a predictor of CIN in breast cancer patients undergoing the chemotherapy cycle. Methods: This research used a prospective and a retrospective longitudinal cohort of breast cancer patients undergo a CAF regimen at Sanglah Hospital Denpasar. The research was conducted on 30 samples for three cycles (90 total cycles). Monocyte data is taken in the first week (days 4 to 9), and neutrophil data is taken in the second week (days 10 to 16). Results: From statistical analysis with interval data scale, we obtained that p 0.001 with Pearson correlation 0.613 for cycle 1, p 0.001 with Pearson correlation 0.611 for cycle 2, and p 0.003 with Pearson correlation 0.522 for cycle 3. Conclusions: In conclusion, post-chemotherapy monocytopenia can be used to predict the occurrence of chemotherapy-induced neutropenia (CIN) with the strongest positive correlation in the first cycle.
ABSTRAK Pola asuh orang tua merupakan salah satu faktor terpenting yang menyebabkan terjadinya perilaku merokok pada remaja.Pola asuh orang tua yang diterapkan tidak selalu direspon baik oleh anak. Sering kali anak memberontak karena kemauan orang tua tidak sejalan dengannya dan membuat anak stress yang mengakibatkan anak berperilaku merokok. Tujuan penelitian ini adalah untuk mengetahui perbedaan perilaku merokok dengan pola asuh demokratis dan pola asuh otoriter pada remaja di Dusun Jetis Desa Wotanngare Kecamatan Kalitidu Kabupaten Bojonegoro.Berdasarkan studi pendahuluan yang dilakukan peneliti dapatkan data di Dusun Jetis Desa Wotanngare Kecamatan Kalitidu Kabupaten Bojonegoro dari 20 remaja terdapat 15 remaja menjadi perokok aktif dengan usia rata – rata 15 – 17 tahun dan dari 15 orang tua 8 orang tua menerapkan pola asuh otoriter, 2 demokratis, 5 permisif.Desain penelitian ini menggunakan metode Cross Sectional dengan populasi semua remaja laki – laki yang merokok dan mempunyai orang tua di Dusun Jetis Desa Wotanngare Kecamatan Kalitidu Kabupaten Bojonegoro. Sampel diambil dengan proses Purposive Sampling. Variabel independen yaitu perilaku merokok, dan variabel dependen adalah pola asuh. Pengumpulan data menggunakan wawancara.Perilaku merokok remaja dapat dicegah apabila faktor-faktor yang menjadikan remaja mempunyai perilaku merokok dapat ditekan, misalkan dalam lingkungan keluarga, orang tua harus menciptakan suasana yang harmonis, sehingga anak tidak menjadi liar dan anak mendapat perhatian yang lebih dari orang tua Kata Kunci : Perilaku Merokok, Pola Asuh Otoriter , Demokratis, Remaja, Orang Tua ABSTRACTPattern foster parent is one of the most important factors that lead to smoking behavior remaja.Pola foster parents who applied is not always responded well by children. Often the children rebelled because of the willingness of parents are not in line with it and make the child behave stress that cause children to smoke. The purpose of this study was to determine differences in smoking behavior with parenting democratic and authoritarian parenting teenagers in Dusun Desa Jetis Wotanngare Kalitidu District of Bojonegoro.Based on preliminary studies conducted by researchers get the data in the hamlet Jetis village Wotanngare District of Kalitidu Bojonegoro of 20 teenagers there are 15 teenagers become active smokers with a mean age - average 15-17 years and from 15 parents 8 parents applying authoritarian parenting, two democratic , 5 permissive.Design of this study using cross sectional method with all adult male population - men who smoke and have parents in Dusun Desa Jetis Wotanngare Kalitidu District of Bojonegoro. Samples were taken by purposive sampling process. The independent variables namely smoking behavior, and the dependent variable is parenting. Data collection using interviews.Adolescent smoking behavior can be avoided if the factors that make adolescents have smoking behavior can be suppressed, for example within the family, parents should create a harmonious atmosphere, so that children do not become wild and the child gets more attention from parents Keywords: Smoking Behavior, Parenting Authoritarian, Democratic, Teens, Parents
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