stay, and ICU and 28-day mortality rate. We compared the characteristics of patients who survived and did not survive after 28 days and their mean arterial pressure (MAP), inotropic score, creatinine, APACHE II score, procalcitonin before and after hemoperfusion treatment. Results: The ICU mortality rate and 28-day mortality rate were 46.34% and 41.6% respectively which are lower than the predicted mortality rate of 49.70% based on the APACHE II score before hemoperfusion treatment and 54% among patients with septic shock. The mean duration of ICU stay is 23.0 AE26.66 and the mean duration of mechanical ventilation is 21.0 AE27.02. There is a significant difference between the non-survivors and the survivors in terms of duration of ICU stay (p ¼0.006), duration of mechanical ventilation (p ¼0.029), number of hemoperfusion treatments (p ¼0.007) and timing of hemoperfusion (p ¼0.006). Among the survivors, 11 (45.83%) had early hemoperfusion ( treatment has significant effect on the duration of ICU stay (p ¼ 0.008) and duration of mechanical ventilation (p ¼0.016). The result shows no significant difference in APACHE II score, inotropic score, hospital stay and renal recovery between early and late hemoperfusion (>48 h) treatment. One patient had bleeding after hemoperfusion treatment. Among the survivors and non-survivors, there was no significant reduction in platelet count before and after hemoperfusion treatment (p ¼0.179, 0.791 respectively). Other reactions such as fever and chills were not observed.Conclusions: Hemoperfusion treatment results in lower ICU and 28day mortality rate. Hemoperfusion has significant effect on the duration of ICU stay and mechanical ventilation. We recommend early hemoperfusion (within 48 hours of diagnosis of sepsis) because it is a significant factor in decreasing ICU and 28-day mortality. Early hemoperfusion treatment also has significant effect on the duration of ICU stay and mechanical ventilation. There were no serious adverse reactions reported during the duration of observation.
fluid compartment after water ingestion. This same error was found in the Tanita machine with the control showing weight gain in the fat compartment after water ingestion. The standard machine was not tested in the dialysis patients as we did not have access to multichannel bioimpedence machines in our unit.Conclusions: Both the expensive multichannel machines and the home bioimpedence scales showed same error in controls after fluid ingestion, with fluid gain recorded in the fat compartment. In dialysis patients, post dialysis fluid loss was recorded as reduction in the fat content, not fluid content (using home bioimpedence scales). Literature search has not revealed details of the body compartment from where the fluid was removed. Fluid storage in dialysis patients needs further study.Potassium (mmol/l) 5.3 (2.9 -8.2)Pulmonary crackles 26% Sodium (mEq/l) 135 (122 -163)Bicarbonates (mmol/l) 12 (5 -23) ISN WCN 2020, ABU DHABI, UAE S318 Kidney International Reports (2020) 5, S1-S392
Introduction: Cardiovascular disease is the leading cause of death and accounts for the majority of morbidity in chronic hemodialysis patients. In addition, hyperparathyroidism is a common complication in these patients and may be responsible in the long term for impaired heart structure and function. The aim of our study was to evaluate the correlation between Hypertrophic cardiomyopathy and hyperparathyroidism in CKD. Methods: This retrospective comparative cohort study enrolled 32 patients (17 male and 15 female with a sex ratio= 1.13) who were started on hemodialysis. Data collected included demographics, Clinical Status and metabolic parameters.Patients are divided into two groups. The first group contains the patients with hypertophic cardiomyopathy and the second group without it.All the patients included in this study gave their consent. Data were entered and analysed using SPSS software. Chi-squared test with a level of significance of 0.05 was used for the qualitative variables.Hyperparathyroidism is defined by a rate greater than nine times the upper limit. Results: The mean age was 50 years old with age ranging between 23 years and 80 years.The mean duration of dialysis was 7 years (range: 6 months to 33 years). The average number of hemodialysis sessions per week was 2 sessions and the session length was three hours and a half. Sixteen patients (50%) had hypertension, 9 patients (28.1%) had diabetes mellitus. The initial nephropathy was diabetic nephropathy, vascular nephropathy, glomerular nephropathy, interstitial nephropathy and indeterminate nephropathy in respectively 15.6%, 25%, 9.3% and 21.8% of cases. During this years of follow-up,2patients (6.25%) died. The cause of death was arrhythmia and septic shock. The average level of Parathyroid hormone (PTH) was 875 Pg/ml; range 469 Pg/ml to 469 Pg/ml. Hyperphosphatemia and hypocalcemia were noted in respectively 25% and 37.5% of cases.The mean of calcium and phosphorus 2.06mmol / L and 1.66mmol / L, respectively. Three patients had surgical parathyroidectomy. All this patients have associaeted hypertrophic cardiomyopathy.The average left ventricular ejection fraction was 60.9%. Hypertrophic cardiomyopathy was noted in 19 patients (39.5%). Seventeen (89.47%) of them have hyperparathyroidism.A significant inverse correlation between serum PTH and the percentage of LV ejection fraction was observed (P= 0.001). A significant correlation of serum PTH with LVH was also found (P= 0.04). Conclusions: Secondary hyperparathyroidism is common in advanced CKD, and first-line medical therapy includes the use of vitamin D agents and calcimimetics. Some patients need parathyroidectomy for medically refractory. Prevention of LVH requires the early detection and correction of specific and non-Cardiovascular risk factors.
dialysis in patients with accidental loss of TDC. The technique described herein, avoids the need to select a new venotomy site, improves patient satisfaction by minimizing procedure related discomfort due to alleviating the need to create a new tunnel, and optimizes resources used for the procedure.
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