This project examined the influence of both public and private secondary schools on the academic performance of students in chemistry and more so, compares their performance in this subject. The private school used here employs Danbo International School. The public School employs Command Secondary School as well. A sample of students offering chemistry was randomly selected from each of the school representing the total population of students offering chemistry. The study involved 67 students with 19 having come in from private (Danbo International) School and 48 students from public (Command Secondary) School. Scores from the student's West African Examination council (WAEC) result were obtained from respective schools and used for analysis. The data collected were subjected to student's t-test statistical analysis at 0.05 significant levels. The result of the study reveals that student in Danbo International School performed relatively better than their counterpart in public (Command Secondary) School. Recommendation was that subjects (science) should be thought with relevant instructional materials in primary schools in order to prepare the pupils for the learning task in secondary schools. Inspectors of education and proprietors should ensure that teachers use instructional materials to teach science subjects.
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