Background: Silver Nanoparticles (AgNP) plays a crucial role in nanoscience, nanotechnology and nanomedicine. AgNP has antibacterial, antifungal, antiviral, anti-inflammatory, anti-antigenic, anticancer and cytotoxic properties. Cytotoxic effects of mouthwashes on the gingival tissue have always been a priority. Pterocarpus santalinus, with the common name of red sandalwood. The aim of the study is to evaluate the cytotoxic effect of red sandal mediated silver nanoparticles mouthwash using brine shrimp lethality assay. Materials and Methods: The mouthwash was prepared using red sandal mediated silver nanoparticles, ethanol, distilled water, sucrose, sodium benzoate, clove oil, sodium dodecyl phosphate with 0.1% in concentration. The methodology includes green synthesis of Red sanders mediated Silver Nanoparticles synthesis followed by tests for Cytotoxic effect using mouthwash. Results: Red sanders mediated silver nanoparticles have high potent cytotoxic potential, it has been proved with the help of brine shrimps. LD50 concentration was obtained to be 80µL, with half the population of nauplii in the respective well surviving post incubation. Conclusion: From the observed result, it has been concluded that Pterocarpus santalinus/red sandal mediated silver nanoparticles mouthwash has a considerably moderate cytotoxic effect. It is a rich source of various potential phytochemicals and is a simple, rapid, stable and cost effective method for nano based medical applications.
Background: Traumatic dental injuries (TDI) are the dental circumstances with high predominance rate and generally connected with impact on children. Dental injury can cause distress and loss of limit has the potential for periapical sequelae, which give an unfriendly impact on the occasion of the extremely durable teeth additionally as the creating impediment. Aim: To assess the prevalence of dental trauma and its association with gender among age groups of 2-6 years. Materials and Methods: The study was carried out among patients who answered to Saveetha Dental College with traumatic injuries such as avulsion, intrusion, extrusion and luxation of age group of 2-6 years. The data was entered into SPSS after the variables were coded. Categorical factors were reported as far as numbers and reference charts were generated using SPSS version 23. The Chi Square test was used to test the statistical analysis of the associations. Results: Among 40 children, who were affected by dental trauma, 62.5% were males and 37.5% are females. As a total count males were higher in count of 23 patients when compared to females 17 patients.
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